Nutrition support in critically ill patients: Current status and practice

Rifat - Latifi, Philip E. Caushaj

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Nutrition support of critically ill patients has entered a new era of nutri-pharmaceutics. This has occurred because of recent gains in knowledge about the role of the gut in immunity and the role of nutrition in modifying the immune response after severe injury. We review the developments in this area that have potential implications for the laboratory in the assessment and monitoring of affected patients. Acute injury evokes a cytokine mediated response leading to postinjury effects that may resolve or progress. The degree of the response is proportional to the injury. It is important to assess the benefits and timing of nutritional interventions. Randomized prospective clinical trials have been done that indicate that even when the mortality is not reduced by such interventions, the morbidity, use of intense resources, and cost of critical care is decreased. The issue of morbidity is related to the development of systemic inflammatory response syndrome (SIRS), organ dysfunction, and multiple organ failure (MOF). Not only has early post- operative enteral feeding been shown to be an alternative to parenteral feeding, but the use of immunomodulators in nutrition support has an additional effect.

Original languageEnglish (US)
Pages (from-to)279-284
Number of pages6
JournalJournal of Clinical Ligand Assay
Volume22
Issue number3
StatePublished - Sep 1999
Externally publishedYes

Fingerprint

Nutrition
Critical Illness
Wounds and Injuries
Morbidity
Systemic Inflammatory Response Syndrome
Multiple Organ Failure
Parenteral Nutrition
Immunologic Factors
Physiologic Monitoring
Enteral Nutrition
Critical Care
Immunity
Randomized Controlled Trials
Cytokines
Costs and Cost Analysis
Mortality
Monitoring
Pharmaceutical Preparations
Costs

Keywords

  • Acute trauma
  • Anabolism
  • Nutritional pharmacology
  • Nutritional risk
  • Stress injury

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology

Cite this

Nutrition support in critically ill patients : Current status and practice. / Latifi, Rifat -; Caushaj, Philip E.

In: Journal of Clinical Ligand Assay, Vol. 22, No. 3, 09.1999, p. 279-284.

Research output: Contribution to journalArticle

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