O-Benzyl-N- t-butyloxycarbonyl- L-serine

Victor J. Heuby, Kenneth W. Ehler

Research output: Contribution to journalComment/debate

20 Scopus citations

Abstract

In solid-phase peptide synthesis, it is desirable to incorporate both serine and threonine as their O-ben-zyl-N-acyloxycarbonyl derivatives.8 Recently, a simple method for preparing O-benzyl-N-if-butyloxycarbonyl-L-threonine was reported.4 On the other hand, methods for preparing O-benzyl-N-i-butyloxycarbonyl-L-serine are very laborious.6-6 The present study reports a simple two-step synthesis of O-benzyl-N-i-butyloxycarbonyl-L-serine from L-serine.

Original languageEnglish (US)
Number of pages1
JournalJournal of Organic Chemistry
Volume35
Issue number5
DOIs
StatePublished - May 1 1970

ASJC Scopus subject areas

  • Organic Chemistry

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