Occurrence and proliferation of antibiotics and antibiotic resistance during wastewater treatment

Majid Neyestani, Eric Dickenson, Jean McLain, Channah Rock, Daniel Gerrity

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Wastewater treatment plants play an important role in protecting human and environmental health from pollution in wastewater, but they are also considered one of the “leading reservoirs” of antibiotic resistance (AR) in the environment. The main objective of this research was to characterize the impact of solids retention time (SRT) in activated sludge systems on the quantity and extent of AR in treated effluent. The quantity of AR was determined based on the number of culturable Gram positive bacteria that were resistant to a suite of single or combined antibiotics at standard clinical concentrations. The extent of AR was determined based on minimum inhibitory concentrations (MICs) of Gram positive isolates. The results showed that longer solids retention times appear to select for antibiotic resistant bacteria, presumably because of the microbial community’s extended exposure to antibiotics in raw wastewater and the greater potential for horizontal gene transfer. In addition, it was observed that longer SRTs potentially promote bacteria that are increasingly resistant to antibiotics. Finally, the research confirms that longer SRTs achieve lower effluent concentrations of trace organic compounds (TOrCs). The reason for this trend appears to be a combination of changes in the microbial community and higher mixed liquor suspended solids concentrations.

Original languageEnglish (US)
Title of host publicationWEFTEC 2016 - 89th Water Environment Federation Annual Technical Exhibition and Conference
PublisherWater Environment Federation
Pages3856-3865
Number of pages10
ISBN (Electronic)9781510870475
StatePublished - Jan 1 2016
Event89th Annual Water Environment Federation Technical Exhibition and Conference, WEFTEC 2016 - New Orleans, United States
Duration: Sep 24 2016Sep 28 2016

Publication series

NameWEFTEC 2016 - 89th Water Environment Federation Annual Technical Exhibition and Conference
Volume7

Conference

Conference89th Annual Water Environment Federation Technical Exhibition and Conference, WEFTEC 2016
CountryUnited States
CityNew Orleans
Period9/24/169/28/16

Keywords

  • Activated sludge
  • Antibiotic resistance
  • Solids retention time
  • Trace organic compound (TOrC)

ASJC Scopus subject areas

  • Ecological Modeling
  • Environmental Chemistry
  • Pollution
  • Waste Management and Disposal
  • Water Science and Technology

Fingerprint Dive into the research topics of 'Occurrence and proliferation of antibiotics and antibiotic resistance during wastewater treatment'. Together they form a unique fingerprint.

  • Cite this

    Neyestani, M., Dickenson, E., McLain, J., Rock, C., & Gerrity, D. (2016). Occurrence and proliferation of antibiotics and antibiotic resistance during wastewater treatment. In WEFTEC 2016 - 89th Water Environment Federation Annual Technical Exhibition and Conference (pp. 3856-3865). (WEFTEC 2016 - 89th Water Environment Federation Annual Technical Exhibition and Conference; Vol. 7). Water Environment Federation.