Ocular manifestations of immunologic and rheumatologic inflammatory disorders

K. Dinowitz, A. J. Aldave, J. R. Lisse, S. D. Trocme

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Exciting new discoveries into the pathophysiological mechanisms of immunologic and inflammatory ocular disease continue. The genetic locus for susceptibility to Behcet's disease and Sjogrens syndrome has been further characterized. Important guidelines for serial slit-lamp examinations for the early detection of iridocyclitis in juvenile rheumatoid arthritis is suggested. In ocular allergy, further investigation of the interaction between mast cell and eosinophil sheds more light on the pathophysiological mechanism of vernal keratoconjunctivitis and vernal corneal ulcers. Unusual manifestations of Behcet's disease, sarcoidosis, scleritis, and Wegener's granulomatosis are reported. A possible pathophysiological mechanism for lacrimal gland destruction in Sjogrens syndrome is presented.

Original languageEnglish (US)
Pages (from-to)91-98
Number of pages8
JournalCurrent Opinion in Ophthalmology
Volume5
Issue number6
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Ophthalmology

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