Odor identification accuracy declines following 24 h of sleep deprivation

William Killgore, Sharon A. McBride

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Brain imaging studies demonstrate that sleep deprivation reduces glucose metabolism and blood flow in the prefrontal cortex, and such reductions are associated with impairments in cognitive functioning. Although some of the greatest metabolic declines occur within the orbitofrontal cortex, little is known about the effects of sleep loss on the types of processes mediated by this region, including emotion, motivation, feeding, and olfaction. The present study tested odor identification accuracy when individuals were well rested and again following 24 h of wakefulness. Relative to rested baseline performance, sleep-deprived individuals demonstrated a significant decline in the ability to identify specific odors on the Smell Identification Test. This decrement in olfactory functioning occurred concomitantly with slowed psychomotor speed and increased ratings of self-reported sleepiness. Performance on a task that required complex mental set shifting did not change significantly following sleep deprivation, suggesting that the decrements in odor identification could not be attributed to task difficulty. Finally, while there was no relationship between subjective sleepiness and odor identification at rested baseline, greater subjective sleepiness was associated with better odor identification ability following 24 h of sleep loss. Possible implications of these findings are discussed.

Original languageEnglish (US)
Pages (from-to)111-116
Number of pages6
JournalJournal of Sleep Research
Volume15
Issue number2
DOIs
StatePublished - Jun 2006
Externally publishedYes

Fingerprint

Sleep Deprivation
Sleep
Aptitude
Smell
Prefrontal Cortex
Wakefulness
Neuroimaging
Blood Glucose
Motivation
Emotions
Identification (Psychology)
Odorants

Keywords

  • Olfaction
  • Olfactory
  • Sleep deprivation
  • Smell identification

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

Cite this

Odor identification accuracy declines following 24 h of sleep deprivation. / Killgore, William; McBride, Sharon A.

In: Journal of Sleep Research, Vol. 15, No. 2, 06.2006, p. 111-116.

Research output: Contribution to journalArticle

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