Odoratin and paucin: Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)

Joseph J. Hoffmann, Shivanand D. Jolad, Sterling J. Torrance, Dori J. Luzbetak, Richard M. Wiedhopf, Jack R. Cole

Research output: Contribution to journalComment/debate

3 Scopus citations

Abstract

An ethanol extract of Baileya pauciradiata exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx and the lymphocytic leukemia test systems. Two constituents responsible for this activity were isolated and identified as odoratin and paucin. Their identities were proven by IR, PMR, and mass spectral data; elemental analysis; preparation of their acetates; and melting‐point determinations. Odoratin was confirmed by comparison with an authentic sample.

Original languageEnglish (US)
Pages (from-to)1633-1634
Number of pages2
JournalJournal of pharmaceutical sciences
Volume67
Issue number11
DOIs
StatePublished - Nov 1978

Keywords

  • Baileya pauciradiata—whole plant ethanol extract, odoratin and paucin isolated and identified
  • Cytotoxic sesquiterpene lactones—odoratin and paucin, isolated from whole plant ethanol extract of Baileya pauciradiata
  • Odoratin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata
  • Paucin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata

ASJC Scopus subject areas

  • Pharmaceutical Science

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