On the rate of genetic adaptation under natural selection

L. R. Ginzburg; R. F. Costantino

doi:10.1016/0022-5193(79)90358-8

On the rate of genetic adaptation under natural selection

L. R. Ginzburg, R. F. Costantino

Ecology and Evolutionary Biology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

For a one locus n-allele genetic model of natural selection two theoretical predictions are obtained: first, that the non-equilibrium average fitness value, W(t) is always between the equilibrium value, W*, and W*-H(p_o, p*) t until finally W(t) = W* and, secondly, that the area bounded by W* and the curve W(t) is equal to H(p₀,p*), the entropy distance between initial (p₀) and equilibrium (p*) gene frequency distributions. The experimental observations corresponding to these predictions are discussed.

Original language	English (US)
Pages (from-to)	307-316
Number of pages	10
Journal	Journal of Theoretical Biology
Volume	77
Issue number	3
DOIs	https://doi.org/10.1016/0022-5193(79)90358-8
State	Published - Apr 7 1979

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
Applied Mathematics

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AB - For a one locus n-allele genetic model of natural selection two theoretical predictions are obtained: first, that the non-equilibrium average fitness value, W(t) is always between the equilibrium value, W*, and W*-H(po, p*) t until finally W(t) = W* and, secondly, that the area bounded by W* and the curve W(t) is equal to H(p0,p*), the entropy distance between initial (p0) and equilibrium (p*) gene frequency distributions. The experimental observations corresponding to these predictions are discussed.

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