One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction

Hao Li, Jian Wang, Timiyin E-Nunu, Liansuo Zu, Wei Jiang, Shaohua Wei, Wei Wang

Research output: Contribution to journalArticlepeer-review

156 Scopus citations

Abstract

A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of α,β-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.

Original languageEnglish (US)
Pages (from-to)507-509
Number of pages3
JournalChemical Communications
Issue number5
DOIs
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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