Optic glomeruli and their inputs in Drosophila share an organizational ground pattern with the antennal lobes

Laiyong Mu, Kei Ito, Jonathan P. Bacon, Nicholas J Strausfeld

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Studying the insect visual system provides important data on the basic neural mechanisms underlying visual processing. As in vertebrates, the first step in visual processing in insects is through a series of retinotopic neurons. Recent studies on flies have found that these converge onto assemblies of columnar neurons in the lobula, the axons of which segregate to project to discrete optic glomeruli in the lateral protocerebrum. This arrangement is much like the fly's olfactory system, in which afferents target uniquely identifiable olfactory glomeruli. Here, whole-cell patch recordings show that even though visual primitives are unreliably encoded by single lobula output neurons because of high synaptic noise, they are reliably encoded by the ensemble of outputs. At a glomerulus, local inter neurons reliably code visual primitives, as do projection neurons conveying information centrally from the glomerulus. These observations demonstrate that in Drosophila, as in other dipterans, optic glomeruli are involved in further reconstructing the fly's visual world. Optic glomeruli and antennal lobe glomeruli share the same ancestral anatomical and functional ground pattern, enabling reliable responses to be extracted from converging sensory inputs.

Original languageEnglish (US)
Pages (from-to)6061-6071
Number of pages11
JournalJournal of Neuroscience
Volume32
Issue number18
DOIs
StatePublished - May 2 2012

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Drosophila
Neurons
Diptera
Insects
Olfactory Bulb
Patch-Clamp Techniques
Axons
Vertebrates
Noise

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Optic glomeruli and their inputs in Drosophila share an organizational ground pattern with the antennal lobes. / Mu, Laiyong; Ito, Kei; Bacon, Jonathan P.; Strausfeld, Nicholas J.

In: Journal of Neuroscience, Vol. 32, No. 18, 02.05.2012, p. 6061-6071.

Research output: Contribution to journalArticle

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