Optical coherence tomography and light-induced fluorescence: Optical slicing plus biochemical probing

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

This chapter describes the combination of optical coherence tomography (most commonly used to visualize the microstructure of tissue) with light-induced fluorescence (which probes the biochemical composition of tissue). This combination has synergistic potential to accurately identify disease, or to elucidate the basic structure and function of tissue. Because the two imaging modalities have very different capabilities and technical requirements, combination into a dual-modality instrument can be challenging, yet can be accomplished in many different configurations. This chapter will examine the motivation for combined systems, several different instrumentation implementations, and example successful applications.

Original languageEnglish (US)
Title of host publicationAdvanced Biophotonics
Subtitle of host publicationTissue Optical Sectioning
PublisherCRC Press
Pages279-298
Number of pages20
ISBN (Electronic)9781439895825
ISBN (Print)9781439895818
StatePublished - Apr 19 2016

Keywords

  • Colon
  • Detectors
  • Eye
  • Fluorescence
  • Imaging instrumentation
  • Light sources
  • Optical coherence tomography
  • Optical fibers
  • Skin

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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