In order to maximize the electrical energy harvested by photovoltaic panels in a setup with fixed angles, it is important to get the angle optimized. In the present work, sunlight availability or sky coverage conditions of year-long period based on ten years’ data are counted in the modeling to optimize the PV panel tilt angles targeting for the maximal energy in a year. The analysis uses precise sunray calculation models. The energy harvested in every 6 minutes by a PV panel is summated for the daily time period from sunrise to sunset when the sun elevation angles are above 5 degree, with the sky-coverage factor multiplied. The results show that the annual solar energy received by a PV solar panel tilted with a fixed angle equal to the local latitude (at Tucson AZ, USA) could reach 2297 kWh/m2 under 10-year averaged sky coverage conditions. However, the gain in the yearly solar energy harvest is expected to be about 4.28%, 7.06%, and 8.42% higher if a PV panel is inclined optimally according to two-season, four-season, and monthly adjustments, respectively, compared to the optimized life-long fixed angle.