Optimizing frequency and pulse shape for ultrasound current source density imaging

Yexian Qin, Zhaohui Wang, Pier Ingram, Qian Li, Russell S. Witte

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Electric field mapping is commonly used to identify irregular conduction pathways in the heart (e.g., arrhythmia) and brain (e.g., epilepsy). A new technique, ultrasound current source density imaging (UCSDI) based on the acoustoelectric (AE) effect, provides an alternative method for current activity mapping in four-dimension with high resolution. The ultrasound transducer frequency and pulse shape significantly affect the sensitivity and spatial resolution of UCSDI. In this paper, we analyze the tradeoff between spatial resolution and sensitivity in UCSDI from two aspects: (1) ultrasound transducer frequency and (2) coded excitation pulses. For frequency dependence, we imaged an electric dipole using ultrasound transducers with different center frequencies (1 MHz and 2.25 MHz) and compared the sensitivity and resolution. For coded excitation, we measured AE signals with chirp excitation at 1 MHz and demonstrated improved sensitivity for chirps (3.5 μV/mA at 1 MHz) compared with square pulse excitation (1.6 μV/mA). Pulse compression was also applied to preserve spatial resolution, demonstrating enhanced detection while preserving spatial resolution.

Original languageEnglish (US)
Title of host publication2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages2138-2141
Number of pages4
DOIs
StatePublished - Dec 1 2011
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: Oct 18 2011Oct 21 2011

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2011 IEEE International Ultrasonics Symposium, IUS 2011
CountryUnited States
CityOrlando, FL
Period10/18/1110/21/11

Keywords

  • ECG
  • acoustoelectric
  • cardiac arrhythmia mapping
  • coded excitation chirps

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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