Opto-electrophoretic detection of bio-molecules using conducting chalcogenide glass sensors

Zhiyong Yang, Megan K. Fah, Kelly A Reynolds, Jonathan D. Sexton, Mark R. Riley, Marie Laure Anne, Bruno Bureau, Pierre Lucas

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Novel telluride glasses with high electrical conductivity, wide infrared transparency and good resistance to crystallization are used to design an opto-electrophoretic sensor for detection and identification of hazardous microorganisms. The sensor is based on an attenuated total reflectance element made of Ge-As-Te glass that serves as bothan optical sensing zone and an electrode for driving the migration of bio-molecules within the evanescent wave of the sensor. An electric field is applied between the optical element and a counter electrode in order to induce the migration of bio-molecules carrying surface charges. The effect of concentration and applied voltage is tested and the migration effect is shown to be reversible upon switching the electric field. The collectedsignal is of high quality and can be used to identify different bacterial genus through statistical spectral analysis. This technique therefore provides the ability to detect hazardous microorganisms with high specificity and high sensitivity in aqueous environments. This has great potential for online monitoring of water quality.

Original languageEnglish (US)
Pages (from-to)26754-26759
Number of pages6
JournalOptics Express
Volume18
Issue number25
DOIs
StatePublished - Dec 6 2010

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microorganisms
conduction
glass
sensors
molecules
water quality
tellurides
electrodes
electric fields
evanescent waves
spectrum analysis
counters
crystallization
reflectance
electrical resistivity
sensitivity
electric potential

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Opto-electrophoretic detection of bio-molecules using conducting chalcogenide glass sensors. / Yang, Zhiyong; Fah, Megan K.; Reynolds, Kelly A; Sexton, Jonathan D.; Riley, Mark R.; Anne, Marie Laure; Bureau, Bruno; Lucas, Pierre.

In: Optics Express, Vol. 18, No. 25, 06.12.2010, p. 26754-26759.

Research output: Contribution to journalArticle

Yang, Zhiyong ; Fah, Megan K. ; Reynolds, Kelly A ; Sexton, Jonathan D. ; Riley, Mark R. ; Anne, Marie Laure ; Bureau, Bruno ; Lucas, Pierre. / Opto-electrophoretic detection of bio-molecules using conducting chalcogenide glass sensors. In: Optics Express. 2010 ; Vol. 18, No. 25. pp. 26754-26759.
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