Origin of Sex for Error Repair II. Rarity and Extreme Environments

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

In a previous paper we studied the simultaneous, and at times conflicting, needs of coping with DNA damage, efficient cell replication, and the avoidance of cell mortality. These selective factors operated on sexual and asexual haploid and diploid populations that were reproductively isolated from one another. We concluded, in part, that a sexual type of cell could not expand from extreme rarity in populations dominated by asexual haploid and diploid cells. In the present paper we show that it is relatively easy for a rare sexual mutant to expand in a population dominated by asexual haploid cells if some matings occur between sexual and asexual cell types. We also study the persistence of sex in high mortality, high damage environments, in which neither the asexual diploid nor haploid can survive. The diploid cannot survive because its lower birth rate cannot overcome mortality and the haploid cannot survive because its birth rate cannot overcome gene damage. Sex can persist in these punishing environments by tuning the parameters of the sexual cycle, and the fusion and splitting rates, into a specified region, thereby reaping both benefits of damage repair and efficient replication.

Original languageEnglish (US)
Pages (from-to)56-81
Number of pages26
JournalTheoretical Population Biology
Volume47
Issue number1
DOIs
StatePublished - Feb 1995

Fingerprint

Haploidy
rarity
repair
Diploidy
haploidy
damage
birth rate
gender
diploidy
mortality
Birth Rate
cells
Mortality
Population
persistence
DNA Damage
DNA
DNA damage
Extreme Environments
gene

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Agricultural and Biological Sciences(all)

Cite this

Origin of Sex for Error Repair II. Rarity and Extreme Environments. / Michod, Richard E; Long, A.

In: Theoretical Population Biology, Vol. 47, No. 1, 02.1995, p. 56-81.

Research output: Contribution to journalArticle

@article{3a21d6bd860d4441b81826a3a0b2dc76,
title = "Origin of Sex for Error Repair II. Rarity and Extreme Environments",
abstract = "In a previous paper we studied the simultaneous, and at times conflicting, needs of coping with DNA damage, efficient cell replication, and the avoidance of cell mortality. These selective factors operated on sexual and asexual haploid and diploid populations that were reproductively isolated from one another. We concluded, in part, that a sexual type of cell could not expand from extreme rarity in populations dominated by asexual haploid and diploid cells. In the present paper we show that it is relatively easy for a rare sexual mutant to expand in a population dominated by asexual haploid cells if some matings occur between sexual and asexual cell types. We also study the persistence of sex in high mortality, high damage environments, in which neither the asexual diploid nor haploid can survive. The diploid cannot survive because its lower birth rate cannot overcome mortality and the haploid cannot survive because its birth rate cannot overcome gene damage. Sex can persist in these punishing environments by tuning the parameters of the sexual cycle, and the fusion and splitting rates, into a specified region, thereby reaping both benefits of damage repair and efficient replication.",
author = "Michod, {Richard E} and A. Long",
year = "1995",
month = "2",
doi = "10.1006/tpbi.1995.1003",
language = "English (US)",
volume = "47",
pages = "56--81",
journal = "Theoretical Population Biology",
issn = "0040-5809",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Origin of Sex for Error Repair II. Rarity and Extreme Environments

AU - Michod, Richard E

AU - Long, A.

PY - 1995/2

Y1 - 1995/2

N2 - In a previous paper we studied the simultaneous, and at times conflicting, needs of coping with DNA damage, efficient cell replication, and the avoidance of cell mortality. These selective factors operated on sexual and asexual haploid and diploid populations that were reproductively isolated from one another. We concluded, in part, that a sexual type of cell could not expand from extreme rarity in populations dominated by asexual haploid and diploid cells. In the present paper we show that it is relatively easy for a rare sexual mutant to expand in a population dominated by asexual haploid cells if some matings occur between sexual and asexual cell types. We also study the persistence of sex in high mortality, high damage environments, in which neither the asexual diploid nor haploid can survive. The diploid cannot survive because its lower birth rate cannot overcome mortality and the haploid cannot survive because its birth rate cannot overcome gene damage. Sex can persist in these punishing environments by tuning the parameters of the sexual cycle, and the fusion and splitting rates, into a specified region, thereby reaping both benefits of damage repair and efficient replication.

AB - In a previous paper we studied the simultaneous, and at times conflicting, needs of coping with DNA damage, efficient cell replication, and the avoidance of cell mortality. These selective factors operated on sexual and asexual haploid and diploid populations that were reproductively isolated from one another. We concluded, in part, that a sexual type of cell could not expand from extreme rarity in populations dominated by asexual haploid and diploid cells. In the present paper we show that it is relatively easy for a rare sexual mutant to expand in a population dominated by asexual haploid cells if some matings occur between sexual and asexual cell types. We also study the persistence of sex in high mortality, high damage environments, in which neither the asexual diploid nor haploid can survive. The diploid cannot survive because its lower birth rate cannot overcome mortality and the haploid cannot survive because its birth rate cannot overcome gene damage. Sex can persist in these punishing environments by tuning the parameters of the sexual cycle, and the fusion and splitting rates, into a specified region, thereby reaping both benefits of damage repair and efficient replication.

UR - http://www.scopus.com/inward/record.url?scp=0029240338&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029240338&partnerID=8YFLogxK

U2 - 10.1006/tpbi.1995.1003

DO - 10.1006/tpbi.1995.1003

M3 - Article

VL - 47

SP - 56

EP - 81

JO - Theoretical Population Biology

JF - Theoretical Population Biology

SN - 0040-5809

IS - 1

ER -