Abstract
After intravenous Candida albicans infection, rats received ornithyl amphotericin methyl ester, amphotericin B, or diluent intravenously. At doses of 0.1 and 0.5 mg/kg, the drugs were equally effective in preventing deaths. However, at doses of 2.0 mg/kg, mortality after treatment with amphotericin B was greater than that after placebo, whereas ornithyl amphotericin methyl ester was fully protective.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 108-109 |
| Number of pages | 2 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 26 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1984 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases
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Galgiani, J. N., & VanWyck, D. B. (1984). Ornithyl amphotericin methyl ester treatment of experimental candidiasis in rats. Antimicrobial Agents and Chemotherapy, 26(1), 108-109. https://doi.org/10.1128/AAC.26.1.108