The OSIRIS-REx mission Navigation Campaign consists of three sub-phases: Approach, Preliminary Survey, and Orbital A. Approach was designed for initial characterization of Bennu while matching Bennu’s heliocentric velocity. Preliminary Survey provided the first spacecraft-based estimate of Bennu’s mass. This phase consisted of five target flybys with a close approach distance of about 7 km. Orbital A was a two-month phase devoted to the Navigation Team learning the close proximity operations dynamics and environment around Bennu and transitioning from center-finding optical navigation to landmark feature-based navigation. This paper provides a detailed summary of the orbit determination performance throughout the Navigation Campaign.