Outcome measures report different aspects of patient function three months following critical care

Linda Denehy, Amy Nordon-Craft, Lara Edbrooke, Daniel C Malone, Sue Berney, Margaret Schenkman, Marc Moss

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.

Objectives: To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.

Design: Cross-sectional data from two clinical trials.

Setting: Two acute care hospitals (Melbourne, Australia and Denver, USA).

Patients: A total of 177 survivors of ICU.

Measurements: Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5×STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.

Main results: 6MWT showed excellent correlation with the TUG (rho = −0.79) and BBS (rho = 0.80); and good correlation with 5×STS (rho = −0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 % of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.

Conclusions: The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.

Original languageEnglish (US)
Pages (from-to)1862-1869
Number of pages8
JournalIntensive Care Medicine
Volume40
Issue number12
DOIs
StatePublished - Nov 21 2014
Externally publishedYes

Fingerprint

Critical Care
Outcome Assessment (Health Care)
Intensive Care Units
Self Report
Survivors
Proxy
Walk Test
Demography
Clinical Trials

Keywords

  • Critical care
  • Patient-reported outcomes
  • Performance-based tests
  • Physical function

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Outcome measures report different aspects of patient function three months following critical care. / Denehy, Linda; Nordon-Craft, Amy; Edbrooke, Lara; Malone, Daniel C; Berney, Sue; Schenkman, Margaret; Moss, Marc.

In: Intensive Care Medicine, Vol. 40, No. 12, 21.11.2014, p. 1862-1869.

Research output: Contribution to journalArticle

Denehy, L, Nordon-Craft, A, Edbrooke, L, Malone, DC, Berney, S, Schenkman, M & Moss, M 2014, 'Outcome measures report different aspects of patient function three months following critical care', Intensive Care Medicine, vol. 40, no. 12, pp. 1862-1869. https://doi.org/10.1007/s00134-014-3513-3
Denehy, Linda ; Nordon-Craft, Amy ; Edbrooke, Lara ; Malone, Daniel C ; Berney, Sue ; Schenkman, Margaret ; Moss, Marc. / Outcome measures report different aspects of patient function three months following critical care. In: Intensive Care Medicine. 2014 ; Vol. 40, No. 12. pp. 1862-1869.
@article{34866b669648495d86bfdad4a620be81,
title = "Outcome measures report different aspects of patient function three months following critical care",
abstract = "Background: Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.Objectives: To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.Design: Cross-sectional data from two clinical trials.Setting: Two acute care hospitals (Melbourne, Australia and Denver, USA).Patients: A total of 177 survivors of ICU.Measurements: Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5×STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.Main results: 6MWT showed excellent correlation with the TUG (rho = −0.79) and BBS (rho = 0.80); and good correlation with 5×STS (rho = −0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 {\%} of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.Conclusions: The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.",
keywords = "Critical care, Patient-reported outcomes, Performance-based tests, Physical function",
author = "Linda Denehy and Amy Nordon-Craft and Lara Edbrooke and Malone, {Daniel C} and Sue Berney and Margaret Schenkman and Marc Moss",
year = "2014",
month = "11",
day = "21",
doi = "10.1007/s00134-014-3513-3",
language = "English (US)",
volume = "40",
pages = "1862--1869",
journal = "Intensive Care Medicine",
issn = "0342-4642",
publisher = "Springer Verlag",
number = "12",

}

TY - JOUR

T1 - Outcome measures report different aspects of patient function three months following critical care

AU - Denehy, Linda

AU - Nordon-Craft, Amy

AU - Edbrooke, Lara

AU - Malone, Daniel C

AU - Berney, Sue

AU - Schenkman, Margaret

AU - Moss, Marc

PY - 2014/11/21

Y1 - 2014/11/21

N2 - Background: Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.Objectives: To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.Design: Cross-sectional data from two clinical trials.Setting: Two acute care hospitals (Melbourne, Australia and Denver, USA).Patients: A total of 177 survivors of ICU.Measurements: Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5×STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.Main results: 6MWT showed excellent correlation with the TUG (rho = −0.79) and BBS (rho = 0.80); and good correlation with 5×STS (rho = −0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 % of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.Conclusions: The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.

AB - Background: Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.Objectives: To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.Design: Cross-sectional data from two clinical trials.Setting: Two acute care hospitals (Melbourne, Australia and Denver, USA).Patients: A total of 177 survivors of ICU.Measurements: Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5×STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.Main results: 6MWT showed excellent correlation with the TUG (rho = −0.79) and BBS (rho = 0.80); and good correlation with 5×STS (rho = −0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 % of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.Conclusions: The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.

KW - Critical care

KW - Patient-reported outcomes

KW - Performance-based tests

KW - Physical function

UR - http://www.scopus.com/inward/record.url?scp=84918797157&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918797157&partnerID=8YFLogxK

U2 - 10.1007/s00134-014-3513-3

DO - 10.1007/s00134-014-3513-3

M3 - Article

VL - 40

SP - 1862

EP - 1869

JO - Intensive Care Medicine

JF - Intensive Care Medicine

SN - 0342-4642

IS - 12

ER -