Outcomes of Comatose Cardiac Arrest Survivors with and Without ST-Segment Elevation Myocardial Infarction Importance of Coronary Angiography

INTCAR-Cardiology Registry

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Objectives The aim of this study was to compare outcomes and coronary angiographic findings in post-cardiac arrest patients with and without ST-segment elevation myocardial infarction (STEMI). Background The 2013 STEMI guidelines recommend performing immediate angiography in resuscitated patients whose initial electrocardiogram shows STEMI. The optimal approach for those without STEMI post-cardiac arrest is less clear. Methods A retrospective evaluation of a post-cardiac arrest registry was performed. Results The database consisted of 746 comatose post-cardiac arrest patients including 198 with STEMI (26.5%) and 548 without STEMI (73.5%). Overall survival was greater in those with STEMI compared with those without (55.1% vs. 41.3%; p = 0.001), whereas in all patients who underwent immediate coronary angiography, survival was similar between those with and without STEMI (54.7% vs. 57.9%; p = 0.60). A culprit vessel was more frequently identified in those with STEMI, but also in one-third of patients without STEMI (80.2% vs. 33.2%; p = 0.001). The majority of culprit vessels were occluded (STEMI, 92.7%; no STEMI, 69.2%; p < 0.0001). An occluded culprit vessel was found in 74.3% of STEMI patients and in 22.9% of no STEMI patients. Among cardiac arrest survivors discharged from the hospital who had presented without STEMI, coronary angiography was associated with better functional outcome (93.3% vs. 78.7%; p < 0.003). Conclusions Early coronary angiography is associated with improved functional outcome among resuscitated patients with and without STEMI. Resuscitated patients with a presumed cardiac etiology appear to benefit from immediate coronary angiography.

Original languageEnglish (US)
Pages (from-to)1031-1040
Number of pages10
JournalJACC: Cardiovascular Interventions
Volume8
Issue number8
DOIs
StatePublished - Jul 1 2015

Keywords

  • cardiac arrest
  • coronary angiography
  • hypothermia
  • post-resuscitation syndrome
  • STEMI

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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