Outsmarting the host

Bacteria modulating the immune response

Matthew D. Woolard, Jeffrey A Frelinger

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Pathogenic bacteria and their hosts have had a two-way conversation for millions of years. This interaction has led to many measure/counter-measure responses by the host and bacteria. The host immune response has developed many mechanisms to neutralize and remove pathogen bacteria. In turn pathogenic bacteria have developed mechanisms to alter and evade the host immune response. We will review some of the mechanisms utilized by bacteria to accomplish this goal. We will also examine the current state of understanding of Francisella tularensis mediated immune evasion.

Original languageEnglish (US)
Pages (from-to)188-202
Number of pages15
JournalImmunologic Research
Volume41
Issue number3 SPEC. ISS.
DOIs
StatePublished - Jul 2008
Externally publishedYes

Fingerprint

Bacteria
Francisella tularensis
Immune Evasion

Keywords

  • Bacterial pathogenesis
  • Francisella
  • Immune evasion
  • Intracellular bacteria

ASJC Scopus subject areas

  • Immunology

Cite this

Outsmarting the host : Bacteria modulating the immune response. / Woolard, Matthew D.; Frelinger, Jeffrey A.

In: Immunologic Research, Vol. 41, No. 3 SPEC. ISS., 07.2008, p. 188-202.

Research output: Contribution to journalArticle

Woolard, Matthew D. ; Frelinger, Jeffrey A. / Outsmarting the host : Bacteria modulating the immune response. In: Immunologic Research. 2008 ; Vol. 41, No. 3 SPEC. ISS. pp. 188-202.
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