Ovarian steroids and premenstrual symptoms: A comparison of group differences and intra-individual patterns

Martha J. Lentz, Nancy Woods, Margaret Heitkemper, Ellen Mitchell, Richard Henker, Joan Shaver

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

To examine the relationship of gonadal hormone and symptom patterns across the menstrual cycle, women screened for 2-3 cycles completed an intensive study cycle; 26 had a low-severity symptoms (LS), 20, a premenstrual syndrome (PMS), and 26, a premenstrual magnification pattern (PMM). All completed daily symptom diaries and collected late afternoon urine samples which were assayed for pregnanediol and estradiol for that cycle. The PMS and PMM groups had significantly more positive cross-correlations of pregnanediol and symptoms than the LS group. Women in all groups had similar levels of estradiol and pregnanediol. Women with PMS and PMM patterns responded to progesterone differently than women with LS patterns: thus the former groups may not benefit from hormone therapies.

Original languageEnglish (US)
Pages (from-to)238-249
Number of pages12
JournalResearch in Nursing and Health
Volume30
Issue number3
DOIs
StatePublished - Jun 1 2007
Externally publishedYes

Keywords

  • Anxiety
  • Depression
  • Emotional states/feelings
  • Estrogen
  • Fluid retention
  • Ovarian hormones
  • Physiological states
  • Premenstrual syndrome
  • Progesterone
  • Women's health

ASJC Scopus subject areas

  • Nursing(all)

Fingerprint Dive into the research topics of 'Ovarian steroids and premenstrual symptoms: A comparison of group differences and intra-individual patterns'. Together they form a unique fingerprint.

  • Cite this