Oxidation and nutritional deficiency in AIDS

Promotion of immune dysfunction for cardiac toxicity?

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Immune dysfunction resulting from HIV infection is a major health threat. As HIV-infected persons survive previously life-threatening infection through the use of effective medical therapies, undernutrition, its immune dysfunction and heart disease have become critical issues in the health care of longer-term survivors. Changes in oxidation and the resulting immune modulation affect their host defenses. The potential role of oxidation and immune dysfunction in HIV-induced heart disease is reviewed. Antioxidant is becoming accepted as interventions in the early and ongoing treatment of HIV disease. Nutritional and hormonal therapy, in coordination with other medical interventions, should extend and improve the quality and quantity of life for individuals infected with HIV. Research about the relationship between nutrition/hormone and development of AIDS is essential for understanding its mechanisms of immune dysfunction and heart disease, and for determining the effectiveness of nutritional and hormonal therapy. The mechanisms and consequences of oxidation and immune dysfunction in HIV/AIDS patients are reviewed with special emphasis on heart disease.

Original languageEnglish (US)
Pages (from-to)417-431
Number of pages15
JournalNutrition Research
Volume18
Issue number2
DOIs
StatePublished - 1998

Fingerprint

Malnutrition
Acquired Immunodeficiency Syndrome
HIV
Heart Diseases
Immune System Diseases
Therapeutics
HIV Infections
Survivors
Antioxidants
Quality of Life
Cardiotoxicity
Hormones
Delivery of Health Care
Health
Infection
Research

Keywords

  • AIDS
  • Antioxidant
  • Cardiac toxicity
  • DHEA
  • Immune dysfunction

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Oxidation and nutritional deficiency in AIDS : Promotion of immune dysfunction for cardiac toxicity? / Liang, Bailin; Larson, Douglas F; Watson, Ronald R.

In: Nutrition Research, Vol. 18, No. 2, 1998, p. 417-431.

Research output: Contribution to journalArticle

@article{26afc83d10cb4f48b8066963e5df3439,
title = "Oxidation and nutritional deficiency in AIDS: Promotion of immune dysfunction for cardiac toxicity?",
abstract = "Immune dysfunction resulting from HIV infection is a major health threat. As HIV-infected persons survive previously life-threatening infection through the use of effective medical therapies, undernutrition, its immune dysfunction and heart disease have become critical issues in the health care of longer-term survivors. Changes in oxidation and the resulting immune modulation affect their host defenses. The potential role of oxidation and immune dysfunction in HIV-induced heart disease is reviewed. Antioxidant is becoming accepted as interventions in the early and ongoing treatment of HIV disease. Nutritional and hormonal therapy, in coordination with other medical interventions, should extend and improve the quality and quantity of life for individuals infected with HIV. Research about the relationship between nutrition/hormone and development of AIDS is essential for understanding its mechanisms of immune dysfunction and heart disease, and for determining the effectiveness of nutritional and hormonal therapy. The mechanisms and consequences of oxidation and immune dysfunction in HIV/AIDS patients are reviewed with special emphasis on heart disease.",
keywords = "AIDS, Antioxidant, Cardiac toxicity, DHEA, Immune dysfunction",
author = "Bailin Liang and Larson, {Douglas F} and Watson, {Ronald R}",
year = "1998",
doi = "10.1016/S0271-5317(98)00031-1",
language = "English (US)",
volume = "18",
pages = "417--431",
journal = "Nutrition Research",
issn = "0271-5317",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Oxidation and nutritional deficiency in AIDS

T2 - Promotion of immune dysfunction for cardiac toxicity?

AU - Liang, Bailin

AU - Larson, Douglas F

AU - Watson, Ronald R

PY - 1998

Y1 - 1998

N2 - Immune dysfunction resulting from HIV infection is a major health threat. As HIV-infected persons survive previously life-threatening infection through the use of effective medical therapies, undernutrition, its immune dysfunction and heart disease have become critical issues in the health care of longer-term survivors. Changes in oxidation and the resulting immune modulation affect their host defenses. The potential role of oxidation and immune dysfunction in HIV-induced heart disease is reviewed. Antioxidant is becoming accepted as interventions in the early and ongoing treatment of HIV disease. Nutritional and hormonal therapy, in coordination with other medical interventions, should extend and improve the quality and quantity of life for individuals infected with HIV. Research about the relationship between nutrition/hormone and development of AIDS is essential for understanding its mechanisms of immune dysfunction and heart disease, and for determining the effectiveness of nutritional and hormonal therapy. The mechanisms and consequences of oxidation and immune dysfunction in HIV/AIDS patients are reviewed with special emphasis on heart disease.

AB - Immune dysfunction resulting from HIV infection is a major health threat. As HIV-infected persons survive previously life-threatening infection through the use of effective medical therapies, undernutrition, its immune dysfunction and heart disease have become critical issues in the health care of longer-term survivors. Changes in oxidation and the resulting immune modulation affect their host defenses. The potential role of oxidation and immune dysfunction in HIV-induced heart disease is reviewed. Antioxidant is becoming accepted as interventions in the early and ongoing treatment of HIV disease. Nutritional and hormonal therapy, in coordination with other medical interventions, should extend and improve the quality and quantity of life for individuals infected with HIV. Research about the relationship between nutrition/hormone and development of AIDS is essential for understanding its mechanisms of immune dysfunction and heart disease, and for determining the effectiveness of nutritional and hormonal therapy. The mechanisms and consequences of oxidation and immune dysfunction in HIV/AIDS patients are reviewed with special emphasis on heart disease.

KW - AIDS

KW - Antioxidant

KW - Cardiac toxicity

KW - DHEA

KW - Immune dysfunction

UR - http://www.scopus.com/inward/record.url?scp=0031885510&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031885510&partnerID=8YFLogxK

U2 - 10.1016/S0271-5317(98)00031-1

DO - 10.1016/S0271-5317(98)00031-1

M3 - Article

VL - 18

SP - 417

EP - 431

JO - Nutrition Research

JF - Nutrition Research

SN - 0271-5317

IS - 2

ER -