Oxygen saturation measurements of blood in retinal vessels during blood loss

Matthew H. Smith, Kurt R.deiminghoff, Lloyd W. Hillman, Russell A Chipman

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

We describe a noninvasive technique and instrumentation for measuring the oxygen saturation of blood in retinal arteries and veins. The measurements are made by shining low-power lasers into the eye, and scanning the beams across a retinal blood vessel. The light reflected and scattered back out of the eye is collected and measured. The oxygen saturation of blood within the vessel is determined by analyzing the vessel absorption profiles at two wavelengths. A complete saturation measurement can be made in less than 1 s, allowing real-time measurement during physiologic changes. The sensitivity of this measurement technique to changes in retinal saturation has been demonstrated through a series of pilot studies in anesthetized swine. We present data indicating that retinal venous oxygen saturation decreases during ongoing blood loss, demonstrating a potential application of an eye oximeter to noninvasively monitor blood loss.

Original languageEnglish (US)
Pages (from-to)296-303
Number of pages8
JournalJournal of Biomedical Optics
Volume3
Issue number3
StatePublished - 1998
Externally publishedYes

Fingerprint

Retinal Vessels
blood vessels
Blood vessels
blood
Blood
Oxygen
saturation
oxygen
Retinal Artery
Retinal Vein
Oximeters
vessels
Blood Vessels
Lasers
Swine
Time measurement
swine
Light
arteries
veins

Keywords

  • Blood loss
  • Eye
  • Noninvasive monitoring
  • Oximetry
  • Retina

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Atomic and Molecular Physics, and Optics
  • Radiological and Ultrasound Technology

Cite this

Oxygen saturation measurements of blood in retinal vessels during blood loss. / Smith, Matthew H.; R.deiminghoff, Kurt; Hillman, Lloyd W.; Chipman, Russell A.

In: Journal of Biomedical Optics, Vol. 3, No. 3, 1998, p. 296-303.

Research output: Contribution to journalArticle

Smith, MH, R.deiminghoff, K, Hillman, LW & Chipman, RA 1998, 'Oxygen saturation measurements of blood in retinal vessels during blood loss', Journal of Biomedical Optics, vol. 3, no. 3, pp. 296-303.
Smith, Matthew H. ; R.deiminghoff, Kurt ; Hillman, Lloyd W. ; Chipman, Russell A. / Oxygen saturation measurements of blood in retinal vessels during blood loss. In: Journal of Biomedical Optics. 1998 ; Vol. 3, No. 3. pp. 296-303.
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