Paper microfluidic detection of salmonella using a smart phone

Tu San Park, Wenyue Li, Jeong Yeol Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We describe a novel demonstration of latex immunoagglutination assay in a paper microfluidics format and subsequent Mie scatter detection using the smart phone's flash and digital camera as optical sensing platform. The background noise was eliminated through careful optimization of Mie scatter parameters: The diameter of latex beads, surfactant concentration, the angle of scatter detection, etc. The detection limit was 10 CFU/mL for Salmonella typhimurium using the paper microfluidics and smart phone. This method can be used for any field deployable assays (demonstrated for foodborne pathogens here; can be used for medical, veterinary, and environmental diagnostics) and is low-cost, easy-to-use, near-real-time and handheld.

Original languageEnglish (US)
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages2002-2004
Number of pages3
ISBN (Print)9780979806452
StatePublished - Jan 1 2012
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: Oct 28 2012Nov 1 2012

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period10/28/1211/1/12

Keywords

  • Latex immunoagglutination
  • Mie scatter
  • Paper microfluidics
  • Salmonella typhimurium

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Park, T. S., Li, W., & Yoon, J. Y. (2012). Paper microfluidic detection of salmonella using a smart phone. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 2002-2004). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.