Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year

Frank W. Roemer, Chian K Kwoh, Michael J. Hannon, David J. Hunter, Felix Eckstein, Jason Grago, Robert M. Boudreau, Martin Englund, Ali Guermazi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 % underwent partial meniscectomy during the year prior to the case-defining visit, compared with none of the knees that did not develop ROA. All (n = 31) knees that had partial meniscectomy and 58.9 % (n = 165) of the knees with prevalent meniscal damage developed ROA (OR = 2.51, 95 % CI [1.73, 3.64]). In knees that developed ROA, partial meniscectomy was associated with an increased risk of worsening cartilage damage (OR = 4.51, 95 % CI [1.53, 13.33]). Conclusions: The probability of having had partial meniscectomy was higher in knees that developed ROA. When looking only at knees that developed ROA, partial meniscectomy was associated with greater risk of worsening cartilage damage. Key Points: • Partial meniscectomy is a controversial treatment option for degenerative meniscal tears. • Partial meniscectomy is strongly associated with incident osteoarthritis within 1 year. • Partial meniscectomy is associated with increased risk of worsening cartilage damage.

Original languageEnglish (US)
Pages (from-to)404-413
Number of pages10
JournalEuropean Radiology
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2017

Fingerprint

Osteoarthritis
Cartilage
Knee
Logistic Models
Knee Osteoarthritis
Tears

Keywords

  • Cartilage loss
  • Meniscus
  • MRI
  • Osteoarthritis
  • Partial meniscectomy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year. / Roemer, Frank W.; Kwoh, Chian K; Hannon, Michael J.; Hunter, David J.; Eckstein, Felix; Grago, Jason; Boudreau, Robert M.; Englund, Martin; Guermazi, Ali.

In: European Radiology, Vol. 27, No. 1, 01.01.2017, p. 404-413.

Research output: Contribution to journalArticle

Roemer, Frank W. ; Kwoh, Chian K ; Hannon, Michael J. ; Hunter, David J. ; Eckstein, Felix ; Grago, Jason ; Boudreau, Robert M. ; Englund, Martin ; Guermazi, Ali. / Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year. In: European Radiology. 2017 ; Vol. 27, No. 1. pp. 404-413.
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abstract = "Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 {\%} underwent partial meniscectomy during the year prior to the case-defining visit, compared with none of the knees that did not develop ROA. All (n = 31) knees that had partial meniscectomy and 58.9 {\%} (n = 165) of the knees with prevalent meniscal damage developed ROA (OR = 2.51, 95 {\%} CI [1.73, 3.64]). In knees that developed ROA, partial meniscectomy was associated with an increased risk of worsening cartilage damage (OR = 4.51, 95 {\%} CI [1.53, 13.33]). Conclusions: The probability of having had partial meniscectomy was higher in knees that developed ROA. When looking only at knees that developed ROA, partial meniscectomy was associated with greater risk of worsening cartilage damage. Key Points: • Partial meniscectomy is a controversial treatment option for degenerative meniscal tears. • Partial meniscectomy is strongly associated with incident osteoarthritis within 1 year. • Partial meniscectomy is associated with increased risk of worsening cartilage damage.",
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AU - Roemer, Frank W.

AU - Kwoh, Chian K

AU - Hannon, Michael J.

AU - Hunter, David J.

AU - Eckstein, Felix

AU - Grago, Jason

AU - Boudreau, Robert M.

AU - Englund, Martin

AU - Guermazi, Ali

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AB - Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 % underwent partial meniscectomy during the year prior to the case-defining visit, compared with none of the knees that did not develop ROA. All (n = 31) knees that had partial meniscectomy and 58.9 % (n = 165) of the knees with prevalent meniscal damage developed ROA (OR = 2.51, 95 % CI [1.73, 3.64]). In knees that developed ROA, partial meniscectomy was associated with an increased risk of worsening cartilage damage (OR = 4.51, 95 % CI [1.53, 13.33]). Conclusions: The probability of having had partial meniscectomy was higher in knees that developed ROA. When looking only at knees that developed ROA, partial meniscectomy was associated with greater risk of worsening cartilage damage. Key Points: • Partial meniscectomy is a controversial treatment option for degenerative meniscal tears. • Partial meniscectomy is strongly associated with incident osteoarthritis within 1 year. • Partial meniscectomy is associated with increased risk of worsening cartilage damage.

KW - Cartilage loss

KW - Meniscus

KW - MRI

KW - Osteoarthritis

KW - Partial meniscectomy

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