Partially redundant functions of two SET-domain polycomb-group proteins in controlling initiation of seed development in Arabidopsis

Dongfang Wang, Mark D. Tyson, Shawn S. Jackson, Ramin Yadegari

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

In Arabidopsis, a complex of Polycomb-group (PcG) proteins functions in the female gametophyte to control the initiation of seed development. Mutations in the PcG genes, including MEDEA (MEA) and FERTILIZATION-INDEPENDENT SEED 2 (FIS2), produce autonomous seeds where endosperm proliferation occurs in the absence of fertilization. By using a yeast two-hybrid screen, we identified MEA and a related protein, SWINGER (SWN), as SET-domain partners of FIS2. Localization data indicated that all three proteins are present in the female gametophyte. Although single-mutant swn plants did not show any defects, swn mutations enhanced the mea mutant phenotype in producing autonomous seeds. Thus, MEA and SWN perform partially redundant functions in controlling the initiation of endosperm development before fertilization in Arabidopsis.

Original languageEnglish (US)
Pages (from-to)13244-13249
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume103
Issue number35
DOIs
StatePublished - Aug 29 2006

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Polycomb-Group Proteins
Arabidopsis
Seeds
Fertilization
Endosperm
Mutation
Proteins
Yeasts
Phenotype
Genes

Keywords

  • Chromatin
  • Endosperm
  • Female gametophyte
  • Fertilization
  • Gene silencing

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Partially redundant functions of two SET-domain polycomb-group proteins in controlling initiation of seed development in Arabidopsis. / Wang, Dongfang; Tyson, Mark D.; Jackson, Shawn S.; Yadegari, Ramin.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 35, 29.08.2006, p. 13244-13249.

Research output: Contribution to journalArticle

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