Pattern recognition for rapid T2 mapping with stimulated echo compensation

Chuan Huang, Maria I Altbach, Georges El Fakhri

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to provide accurate T2 estimates with indirect echo compensation. However, the iterative nonlinear least square fitting is computationally expensive and the T2 map generation time is long. In this work, we present a pattern recognition T2 mapping technique based on the SEPG model that can be performed with a single pre-computed dictionary for any arbitrary echo spacing. Almost identical T2 and B1 maps were obtained from in vivo data using the proposed technique compared to conventional iterative nonlinear least square fitting, while the computation time was reduced by more than 14-fold.

Original languageEnglish (US)
Pages (from-to)969-974
Number of pages6
JournalMagnetic Resonance Imaging
Volume32
Issue number7
DOIs
StatePublished - 2014

Fingerprint

Least-Squares Analysis
Pattern recognition
Glossaries
Contamination
Compensation and Redress

Keywords

  • Indirect echoes
  • MR parameter
  • Quantitative MRI
  • Slice imperfection
  • Stimulated echoes
  • T2 mapping

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Biomedical Engineering
  • Medicine(all)

Cite this

Pattern recognition for rapid T2 mapping with stimulated echo compensation. / Huang, Chuan; Altbach, Maria I; El Fakhri, Georges.

In: Magnetic Resonance Imaging, Vol. 32, No. 7, 2014, p. 969-974.

Research output: Contribution to journalArticle

Huang, Chuan ; Altbach, Maria I ; El Fakhri, Georges. / Pattern recognition for rapid T2 mapping with stimulated echo compensation. In: Magnetic Resonance Imaging. 2014 ; Vol. 32, No. 7. pp. 969-974.
@article{924a49fc4e8c440c84f80281e0a38974,
title = "Pattern recognition for rapid T2 mapping with stimulated echo compensation",
abstract = "Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to provide accurate T2 estimates with indirect echo compensation. However, the iterative nonlinear least square fitting is computationally expensive and the T2 map generation time is long. In this work, we present a pattern recognition T2 mapping technique based on the SEPG model that can be performed with a single pre-computed dictionary for any arbitrary echo spacing. Almost identical T2 and B1 maps were obtained from in vivo data using the proposed technique compared to conventional iterative nonlinear least square fitting, while the computation time was reduced by more than 14-fold.",
keywords = "Indirect echoes, MR parameter, Quantitative MRI, Slice imperfection, Stimulated echoes, T2 mapping",
author = "Chuan Huang and Altbach, {Maria I} and {El Fakhri}, Georges",
year = "2014",
doi = "10.1016/j.mri.2014.04.014",
language = "English (US)",
volume = "32",
pages = "969--974",
journal = "Magnetic Resonance Imaging",
issn = "0730-725X",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Pattern recognition for rapid T2 mapping with stimulated echo compensation

AU - Huang, Chuan

AU - Altbach, Maria I

AU - El Fakhri, Georges

PY - 2014

Y1 - 2014

N2 - Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to provide accurate T2 estimates with indirect echo compensation. However, the iterative nonlinear least square fitting is computationally expensive and the T2 map generation time is long. In this work, we present a pattern recognition T2 mapping technique based on the SEPG model that can be performed with a single pre-computed dictionary for any arbitrary echo spacing. Almost identical T2 and B1 maps were obtained from in vivo data using the proposed technique compared to conventional iterative nonlinear least square fitting, while the computation time was reduced by more than 14-fold.

AB - Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to provide accurate T2 estimates with indirect echo compensation. However, the iterative nonlinear least square fitting is computationally expensive and the T2 map generation time is long. In this work, we present a pattern recognition T2 mapping technique based on the SEPG model that can be performed with a single pre-computed dictionary for any arbitrary echo spacing. Almost identical T2 and B1 maps were obtained from in vivo data using the proposed technique compared to conventional iterative nonlinear least square fitting, while the computation time was reduced by more than 14-fold.

KW - Indirect echoes

KW - MR parameter

KW - Quantitative MRI

KW - Slice imperfection

KW - Stimulated echoes

KW - T2 mapping

UR - http://www.scopus.com/inward/record.url?scp=84904048490&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904048490&partnerID=8YFLogxK

U2 - 10.1016/j.mri.2014.04.014

DO - 10.1016/j.mri.2014.04.014

M3 - Article

C2 - 24853466

AN - SCOPUS:84904048490

VL - 32

SP - 969

EP - 974

JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

SN - 0730-725X

IS - 7

ER -