Peptide self-assembly as a model of proteins in the pre-genomic world

Indraneel Ghosh, Jean Chmielewski

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.

Original languageEnglish (US)
Pages (from-to)640-644
Number of pages5
JournalCurrent Opinion in Chemical Biology
Volume8
Issue number6
DOIs
StatePublished - Dec 2004

Fingerprint

Self assembly
Peptides
Nucleotide Aptamers
Catalytic RNA
Proteins
Biopolymers
Amides
Salts
Switches

ASJC Scopus subject areas

  • Biochemistry

Cite this

Peptide self-assembly as a model of proteins in the pre-genomic world. / Ghosh, Indraneel; Chmielewski, Jean.

In: Current Opinion in Chemical Biology, Vol. 8, No. 6, 12.2004, p. 640-644.

Research output: Contribution to journalArticle

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