Performance comparison of different compact NIR fluorescent imaging systems with Goggle display for intraoperative image-guidance

Shengkui Gao, Suman Mondal, Nan Zhu, Rongguang Liang, Samuel Achilefu, Viktor Gruev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Near-infrared (NIR) fluorescent imaging system has been widely used for intraoperative image-guided application. In this paper, we present performance comparison from three compact NIR fluorescence imaging system prototypes with goggle display that we developed for intraoperative guidance: threshold detection based two camera system, feature matching based three cameras system and miniature beam-splitter single camera system. Their performance is evaluated according to sensitivity regarding different ICG concentrations, accuracy of image overlay between NIR-visible channels, compactness and practicability in intraoperative use. The comparison results show great potentials of using these NIR fluorescence imaging systems to improve user experience and surgical outcomes in intraoperative use.

Original languageEnglish (US)
Title of host publicationAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII
EditorsTuan Vo-Dinh, Anita Mahadevan-Jansen, Warren S. Grundfest
PublisherSPIE
ISBN (Electronic)9781628414035
DOIs
StatePublished - Jan 1 2015
EventAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII - San Francisco, United States
Duration: Feb 8 2015Feb 10 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9313
ISSN (Print)1605-7422

Other

OtherAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII
CountryUnited States
CitySan Francisco
Period2/8/152/10/15

Keywords

  • CMOS imaging sensor
  • HMD goggle
  • Image guided surgery
  • NIR fluorescence
  • image overlay
  • threshold detection

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Gao, S., Mondal, S., Zhu, N., Liang, R., Achilefu, S., & Gruev, V. (2015). Performance comparison of different compact NIR fluorescent imaging systems with Goggle display for intraoperative image-guidance. In T. Vo-Dinh, A. Mahadevan-Jansen, & W. S. Grundfest (Eds.), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII [931304] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9313). SPIE. https://doi.org/10.1117/12.2079446