Periparturient endocrine changes of conceptus and maternal units in Holstein heifers bearing genetically different conceptuses.

L. A. Guilbault, W. W. Thatcher, Robert J Collier, C. J. Wilcox

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Holstein heifers (n = 21) were balanced across sires and assigned to three service-sire-breed groups in which heifers were inseminated artificially to either purebred Angus (n = 7), Holstein (n = 7) or Brahman (n = 7) bulls. Semen from four bulls was used for each service sire-breed group. Blood samples were collected from a jugular vein thrice weekly from d 160 to 265 of pregnancy, daily thereafter until 15 d postpartum, and then thrice weekly until d 60 postpartum. Concentrations of progesterone, estrone, estradiol, and estrone sulfate from 23 d prepartum to parturition, and of 15-keto-13,14-dihydro-prostaglandin F2 alpha (PGFM) from 2 d prepartum to d 15 postpartum were measured by radioimmunoassay. Heifers within the Brahman-service-sire group had longer gestations (P less than .05) than those of Holstein- or Angus-service-sire groups (285.0 vs 278.7), 279.0 d). Calf birth weight was lower (P less than .05) in Angus- than Holstein- and Brahman-service-sire groups (30.6 vs 36.1, 43.4 kg). Daily trends of prepartum maternal progesterone concentrations were approximately 1 ng/ml lower (P less than .01) in Angus- than Holstein- or Brahman-service-sire groups until luteolysis occurred. Heifers bearing crossbred Angus conceptuses had lower daily trends of prepartum estrogens concentrations (P less than .01), whereas heifers of the Holstein- and, even more dramatically, of the Brahman-service-sire groups had a higher magnitude and greater rise of plasma estrogens concentrations between d -10 and -1 prepartum (less than .01). Postpartum mean concentrations (P less than .05) and response curves of PGFM were lower (P less than .01) in the Angus- than in the Holstein- or Brahman-service-sire groups. Calf birth weights were correlated with least-squares means for maternal concentrations of prepartum estrone (r = .57), estradiol (r = .59) and estrone sulfate (r = .64) and postpartum maternal concentrations of PGFM (r = .56). Functional responses of the conceptus (e.g., estrogens) and maternal units (e.g., progesterone and PGFM) were influenced by conceptus genotype during the periparturient period.

Original languageEnglish (US)
Pages (from-to)1505-1515
Number of pages11
JournalJournal of Animal Science
Volume61
Issue number6
StatePublished - Dec 1985
Externally publishedYes

Fingerprint

conceptus
Postpartum Period
sires
heifers
Holstein
Brahman
Mothers
Angus
Estrogens
estrone
Progesterone
Estrone
estrogens
Birth Weight
progesterone
Luteolysis
Pregnancy
Dinoprost
Jugular Veins
birth weight

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Periparturient endocrine changes of conceptus and maternal units in Holstein heifers bearing genetically different conceptuses. / Guilbault, L. A.; Thatcher, W. W.; Collier, Robert J; Wilcox, C. J.

In: Journal of Animal Science, Vol. 61, No. 6, 12.1985, p. 1505-1515.

Research output: Contribution to journalArticle

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