Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations


Single-photon emission computed tomography (SPECT) is an inverse problem in which one wants to determine the distribution of a radionuclide from a set of measured projections. Like most inverse problems, it is ill-posed and does not admit of an exact solution. In this paper we review various methods from the literature on inverse problems that are applicable to SPECT. Topics considered include the discrete representation of continuous objects, the intrinsic dimensionality of an object, null functions, the role of prior information, and various reconstruction principles, including maximum likelihood, least squares, and Bayesian methods.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Number of pages6
ISBN (Print)0892527064
Publication statusPublished - 1986


ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Barrett, H. H. (1986). PERSPECTIVES ON SPECT. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 671, pp. 178-183). SPIE.