Pet ownership and cancer risk in the women's health initiative

David O. Garcia, Eric M. Lander, Betsy C. Wertheim, Joann E. Manson, Stella L. Volpe, Rowan T. Chlebowski, Marcia L. Stefanick, Lawrence S. Lessin, Lewis H. Kuller, Cynthia Thomson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Pet ownership and cancer are both highly prevalent in the United States. Evidence suggests that associations may exist between this potentially modifiable factor and cancer prevention, though studies are sparse. The present report examined whether pet ownership (dog, cat, or bird) is associated with lower risk for total cancer and site-specific obesityrelated cancers. Methods: This was a prospective analysis of 123,560 participants (20,981 dog owners; 19,288 cat owners; 1,338 bird owners; and 81,953 non-pet owners) enrolled in the Women's Health Initiative observational study and clinical trials. Cox proportional hazards models were used to estimate HR and 95% confidence intervals for the association between pet ownership and cancer, adjusted for potential confounders. Results: There were no significant relationships between ownership of a dog, cat, or bird and incidence of cancer overall. When site-specific cancers were examined, no associations were observed after adjustment for multiple comparisons. Conclusion: Pet ownership had no association with overall cancer incidence. Impact: This is the first large epidemiologic study to date to explore relationships between pet ownership and cancer risk, as well as associated risks for individual cancer types. This study requires replication in other sizable, diverse cohorts.

Original languageEnglish (US)
Pages (from-to)1311-1316
Number of pages6
JournalCancer Epidemiology Biomarkers and Prevention
Volume25
Issue number9
DOIs
StatePublished - Sep 1 2016

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Ownership
Pets
Women's Health
Neoplasms
Birds
Cats
Dogs
Incidence
Proportional Hazards Models
Observational Studies
Epidemiologic Studies
Clinical Trials
Confidence Intervals

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

Cite this

Garcia, D. O., Lander, E. M., Wertheim, B. C., Manson, J. E., Volpe, S. L., Chlebowski, R. T., ... Thomson, C. (2016). Pet ownership and cancer risk in the women's health initiative. Cancer Epidemiology Biomarkers and Prevention, 25(9), 1311-1316. https://doi.org/10.1158/1055-9965.EPI-16-0218

Pet ownership and cancer risk in the women's health initiative. / Garcia, David O.; Lander, Eric M.; Wertheim, Betsy C.; Manson, Joann E.; Volpe, Stella L.; Chlebowski, Rowan T.; Stefanick, Marcia L.; Lessin, Lawrence S.; Kuller, Lewis H.; Thomson, Cynthia.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 25, No. 9, 01.09.2016, p. 1311-1316.

Research output: Contribution to journalArticle

Garcia, DO, Lander, EM, Wertheim, BC, Manson, JE, Volpe, SL, Chlebowski, RT, Stefanick, ML, Lessin, LS, Kuller, LH & Thomson, C 2016, 'Pet ownership and cancer risk in the women's health initiative', Cancer Epidemiology Biomarkers and Prevention, vol. 25, no. 9, pp. 1311-1316. https://doi.org/10.1158/1055-9965.EPI-16-0218
Garcia DO, Lander EM, Wertheim BC, Manson JE, Volpe SL, Chlebowski RT et al. Pet ownership and cancer risk in the women's health initiative. Cancer Epidemiology Biomarkers and Prevention. 2016 Sep 1;25(9):1311-1316. https://doi.org/10.1158/1055-9965.EPI-16-0218
Garcia, David O. ; Lander, Eric M. ; Wertheim, Betsy C. ; Manson, Joann E. ; Volpe, Stella L. ; Chlebowski, Rowan T. ; Stefanick, Marcia L. ; Lessin, Lawrence S. ; Kuller, Lewis H. ; Thomson, Cynthia. / Pet ownership and cancer risk in the women's health initiative. In: Cancer Epidemiology Biomarkers and Prevention. 2016 ; Vol. 25, No. 9. pp. 1311-1316.
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