Phage-bacteria infection networks

Joshua S. Weitz, Timothée Poisot, Justin R. Meyer, Cesar O. Flores, Sergi Valverde, Matthew Sullivan, Michael E. Hochberg

Research output: Contribution to journalArticle

124 Citations (Scopus)

Abstract

Phage and their bacterial hosts are the most abundant and genetically diverse group of organisms on the planet. Given their dominance, it is no wonder that many recent studies have found that phage-bacteria interactions strongly influence global biogeochemical cycles, incidence of human diseases, productivity of industrial microbial commodities, and patterns of microbial genome diversity. Unfortunately, given the extreme diversity and complexity of microbial communities, traditional analyses fail to characterize interaction patterns and underlying processes. Here, we review emerging systems approaches that combine empirical data with rigorous theoretical analysis to study phage-bacterial interactions as networks rather than as coupled interactions in isolation.

Original languageEnglish (US)
Pages (from-to)82-91
Number of pages10
JournalTrends in Microbiology
Volume21
Issue number2
DOIs
StatePublished - Feb 2013

Fingerprint

Bacteriophages
Bacteria
Infection
Microbial Genome
Planets
Incidence

Keywords

  • Biodiversity
  • Complex networks
  • Ecosystem
  • Functional diversity
  • Microbial ecology
  • Theory

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology
  • Virology

Cite this

Weitz, J. S., Poisot, T., Meyer, J. R., Flores, C. O., Valverde, S., Sullivan, M., & Hochberg, M. E. (2013). Phage-bacteria infection networks. Trends in Microbiology, 21(2), 82-91. https://doi.org/10.1016/j.tim.2012.11.003

Phage-bacteria infection networks. / Weitz, Joshua S.; Poisot, Timothée; Meyer, Justin R.; Flores, Cesar O.; Valverde, Sergi; Sullivan, Matthew; Hochberg, Michael E.

In: Trends in Microbiology, Vol. 21, No. 2, 02.2013, p. 82-91.

Research output: Contribution to journalArticle

Weitz, JS, Poisot, T, Meyer, JR, Flores, CO, Valverde, S, Sullivan, M & Hochberg, ME 2013, 'Phage-bacteria infection networks', Trends in Microbiology, vol. 21, no. 2, pp. 82-91. https://doi.org/10.1016/j.tim.2012.11.003
Weitz JS, Poisot T, Meyer JR, Flores CO, Valverde S, Sullivan M et al. Phage-bacteria infection networks. Trends in Microbiology. 2013 Feb;21(2):82-91. https://doi.org/10.1016/j.tim.2012.11.003
Weitz, Joshua S. ; Poisot, Timothée ; Meyer, Justin R. ; Flores, Cesar O. ; Valverde, Sergi ; Sullivan, Matthew ; Hochberg, Michael E. / Phage-bacteria infection networks. In: Trends in Microbiology. 2013 ; Vol. 21, No. 2. pp. 82-91.
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