Abstract
Objective: This study aimed to test the feasibility of a 12-month weight loss intervention using telephone-based counseling plus community-situated physical activity (PA) in female breast cancer (BC) and colorectal cancer (CRC) survivors. Methods: This multisite cooperative group study enrolled sedentary, female, postmenopausal BC and CRC survivors with BMI ≥ 25 kg/m2 to receive 12-month fitness center memberships and telephone counseling encouraging 150 min/wk of PA and a 500-kcal/ddecrease in energy intake. Feasibility criteria included accrual, adherence, and retention. Target weight loszs was ≥ 5%. Results: Among 25 BC survivors, median baseline BMI was 37.2 (range: 27.7-54.6), accrual occurred in 10 months, 60% and 28% met diet and exercise goals, 80% provided 12-month measures, and average weight loss was 7.6% (95% CI: −3.9%, 19.2%). Among 23 CRC survivors, median BMI was 31.8 (range: 26.4-48.7), accrual occurred in 24 months, 61% and 17% met diet and exercise goals, 87% provided measures, and average weight loss was 2.5% (95% CI: −8.2%, 13.3%). Conclusions: It is feasible to recruit and retain BC survivors in a cooperative group diet and PA weight loss trial. BC survivors achieved clinically meaningful weight loss but did not meet a priori adherence goals. In CRC survivors, recruitment was more difficult, and the intervention was less effective.
| Original language | English (US) |
|---|---|
| Journal | Obesity |
| DOIs | |
| State | Accepted/In press - Jan 1 2018 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Endocrinology, Diabetes and Metabolism
- Endocrinology
- Nutrition and Dietetics
Cite this
Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008). / Greenlee, Heather; Lew, Danika L.; Hershman, Dawn L.; Newman, Vicky A.; Hansen, Lisa; Hartman, Sheri J.; Korner, Judith; Shi, Zaixing; Sardo Molmenti, Christine L.; Sayegh, Antoine; Fehrenbacher, Lou; Lo, Shelly; Klemp, Jennifer; Rinn, Kristine; Robertson, John M.; Unger, Joseph; Gralow, Julie; Albain, Kathy; Krouse, Robert S; Fabian, Carol.
In: Obesity, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008)
AU - Greenlee, Heather
AU - Lew, Danika L.
AU - Hershman, Dawn L.
AU - Newman, Vicky A.
AU - Hansen, Lisa
AU - Hartman, Sheri J.
AU - Korner, Judith
AU - Shi, Zaixing
AU - Sardo Molmenti, Christine L.
AU - Sayegh, Antoine
AU - Fehrenbacher, Lou
AU - Lo, Shelly
AU - Klemp, Jennifer
AU - Rinn, Kristine
AU - Robertson, John M.
AU - Unger, Joseph
AU - Gralow, Julie
AU - Albain, Kathy
AU - Krouse, Robert S
AU - Fabian, Carol
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Objective: This study aimed to test the feasibility of a 12-month weight loss intervention using telephone-based counseling plus community-situated physical activity (PA) in female breast cancer (BC) and colorectal cancer (CRC) survivors. Methods: This multisite cooperative group study enrolled sedentary, female, postmenopausal BC and CRC survivors with BMI ≥ 25 kg/m2 to receive 12-month fitness center memberships and telephone counseling encouraging 150 min/wk of PA and a 500-kcal/ddecrease in energy intake. Feasibility criteria included accrual, adherence, and retention. Target weight loszs was ≥ 5%. Results: Among 25 BC survivors, median baseline BMI was 37.2 (range: 27.7-54.6), accrual occurred in 10 months, 60% and 28% met diet and exercise goals, 80% provided 12-month measures, and average weight loss was 7.6% (95% CI: −3.9%, 19.2%). Among 23 CRC survivors, median BMI was 31.8 (range: 26.4-48.7), accrual occurred in 24 months, 61% and 17% met diet and exercise goals, 87% provided measures, and average weight loss was 2.5% (95% CI: −8.2%, 13.3%). Conclusions: It is feasible to recruit and retain BC survivors in a cooperative group diet and PA weight loss trial. BC survivors achieved clinically meaningful weight loss but did not meet a priori adherence goals. In CRC survivors, recruitment was more difficult, and the intervention was less effective.
AB - Objective: This study aimed to test the feasibility of a 12-month weight loss intervention using telephone-based counseling plus community-situated physical activity (PA) in female breast cancer (BC) and colorectal cancer (CRC) survivors. Methods: This multisite cooperative group study enrolled sedentary, female, postmenopausal BC and CRC survivors with BMI ≥ 25 kg/m2 to receive 12-month fitness center memberships and telephone counseling encouraging 150 min/wk of PA and a 500-kcal/ddecrease in energy intake. Feasibility criteria included accrual, adherence, and retention. Target weight loszs was ≥ 5%. Results: Among 25 BC survivors, median baseline BMI was 37.2 (range: 27.7-54.6), accrual occurred in 10 months, 60% and 28% met diet and exercise goals, 80% provided 12-month measures, and average weight loss was 7.6% (95% CI: −3.9%, 19.2%). Among 23 CRC survivors, median BMI was 31.8 (range: 26.4-48.7), accrual occurred in 24 months, 61% and 17% met diet and exercise goals, 87% provided measures, and average weight loss was 2.5% (95% CI: −8.2%, 13.3%). Conclusions: It is feasible to recruit and retain BC survivors in a cooperative group diet and PA weight loss trial. BC survivors achieved clinically meaningful weight loss but did not meet a priori adherence goals. In CRC survivors, recruitment was more difficult, and the intervention was less effective.
UR - http://www.scopus.com/inward/record.url?scp=85053409568&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85053409568&partnerID=8YFLogxK
U2 - 10.1002/oby.22269
DO - 10.1002/oby.22269
M3 - Article
C2 - 30272836
AN - SCOPUS:85053409568
JO - Obesity
JF - Obesity
SN - 1930-7381
ER -