Phototriggering of geometric dendrimer disassembly

An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers

Michael L. Szalai, Dominic V Mcgrath

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Dendrimers capable of phototriggered disassembly were prepared up to the second-generation using an improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. It was found that disassembly proceeds to 75-80% completion after 2 h of irradiation at 310 nm for all molecules studied. The lack of complete reaction is attributed to an inefficient photochemical deprotection process rather than the disassembly itself.

Original languageEnglish (US)
Pages (from-to)7261-7266
Number of pages6
JournalTetrahedron
Volume60
Issue number34
DOIs
StatePublished - Aug 16 2004

Fingerprint

Dendrimers
Phenol
Photochemical Processes
Irradiation
Molecules
4-hydroxybenzyl alcohol

Keywords

  • Dendrimers
  • Disassembly
  • Tetrahydrofuran

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Phototriggering of geometric dendrimer disassembly : An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. / Szalai, Michael L.; Mcgrath, Dominic V.

In: Tetrahedron, Vol. 60, No. 34, 16.08.2004, p. 7261-7266.

Research output: Contribution to journalArticle

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