Physical symptoms, coping styles and quality of life in recurrent ovarian cancer: A prospective population-based study over the last year of life

M. A. Price, Melanie L Bell, D. W. Sommeijer, M. Friedlander, M. R. Stockler, A. Defazio, P. M. Webb, P. N. Butow

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Objective The aim of this study was to describe the trajectory of physical symptoms, coping styles and quality of life (QoL) and the relationship between coping and QoL over the last year of life in women with recurrent ovarian cancer. Methods The patient cohort were women recruited to the Australian Ovarian Cancer Study who subsequently experienced recurrent, invasive ovarian cancer and completed at least one psychosocial assessment (optimism, minimisation, hopelessness/helplessness, QoL) during the last year of life (n = 217). Results QoL declined sharply from six months before death. Lack of energy was the most prevalent symptom over three measurement periods (67-92%) and also the most severe. Anorexia (36-55%), abdominal swelling (33-58%), nausea (26-47%) and pain (26-43%) all increased in prevalence and severity towards the end of life. Higher optimism (p = 0.009), higher minimisation (p = 0.003) and lower helplessness/hopelessness (p = 0.03) at baseline were significant predictors of subsequent higher QoL. Conclusions Progressive deterioration in quality of life may be an indicator of death within about six months and therefore should be an important consideration in decisions about subsequent treatment. Coping styles which independently predicted subsequent changes in QoL could potentially be targeted by interventions to minimise worsening QoL.

Original languageEnglish (US)
Pages (from-to)162-168
Number of pages7
JournalGynecologic Oncology
Volume130
Issue number1
DOIs
StatePublished - Jul 2013
Externally publishedYes

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Ovarian Neoplasms
Quality of Life
Population
Anorexia
Nausea
Pain

Keywords

  • Coping
  • End of life
  • Ovarian cancer
  • Psychosocial
  • Quality of life
  • Symptoms

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Physical symptoms, coping styles and quality of life in recurrent ovarian cancer : A prospective population-based study over the last year of life. / Price, M. A.; Bell, Melanie L; Sommeijer, D. W.; Friedlander, M.; Stockler, M. R.; Defazio, A.; Webb, P. M.; Butow, P. N.

In: Gynecologic Oncology, Vol. 130, No. 1, 07.2013, p. 162-168.

Research output: Contribution to journalArticle

Price, M. A. ; Bell, Melanie L ; Sommeijer, D. W. ; Friedlander, M. ; Stockler, M. R. ; Defazio, A. ; Webb, P. M. ; Butow, P. N. / Physical symptoms, coping styles and quality of life in recurrent ovarian cancer : A prospective population-based study over the last year of life. In: Gynecologic Oncology. 2013 ; Vol. 130, No. 1. pp. 162-168.
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