Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids

C. D. Deal, N. Stromberg, G. Nyberg, S. Normark, K. A. Karlsson, Magdalene "Maggie" So

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The adherence process in pathogenesis involves the attachment of bacteria to structures present on eukaryotic cell surfaces. To investigate components necessary for this interaction, we have characterized the binding of N. gonorrhoeae to eukaryotic glycolipids immobilized on thin layer chromatograms. The gonococci specifically bind to a subset of glycolipids consisting of lactosylceramide, gangliotriosylceramide, and gangliotetraosylceramide. This binding was identified in both piliated and nonpiliated cells, and is postulated to be mediated by a nonpilin lectin-like adhesin protein.

Original languageEnglish (US)
Pages (from-to)425-430
Number of pages6
JournalAntonie van Leeuwenhoek
Volume53
Issue number6
DOIs
StatePublished - Nov 1987
Externally publishedYes

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Fimbriae Proteins
Neisseria gonorrhoeae
Glycolipids
Eukaryotic Cells
Lectins
Bacteria
Proteins
ganglio-N-triaosylceramide
CDw17 antigen
G(A1) ganglioside

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids. / Deal, C. D.; Stromberg, N.; Nyberg, G.; Normark, S.; Karlsson, K. A.; So, Magdalene "Maggie".

In: Antonie van Leeuwenhoek, Vol. 53, No. 6, 11.1987, p. 425-430.

Research output: Contribution to journalArticle

Deal, CD, Stromberg, N, Nyberg, G, Normark, S, Karlsson, KA & So, MM 1987, 'Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids', Antonie van Leeuwenhoek, vol. 53, no. 6, pp. 425-430. https://doi.org/10.1007/BF00415497
Deal, C. D. ; Stromberg, N. ; Nyberg, G. ; Normark, S. ; Karlsson, K. A. ; So, Magdalene "Maggie". / Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids. In: Antonie van Leeuwenhoek. 1987 ; Vol. 53, No. 6. pp. 425-430.
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