Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids

C. D. Deal, N. Stromberg, G. Nyberg, S. Normark, K. A. Karlsson, M. So

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The adherence process in pathogenesis involves the attachment of bacteria to structures present on eukaryotic cell surfaces. To investigate components necessary for this interaction, we have characterized the binding of N. gonorrhoeae to eukaryotic glycolipids immobilized on thin layer chromatograms. The gonococci specifically bind to a subset of glycolipids consisting of lactosylceramide, gangliotriosylceramide, and gangliotetraosylceramide. This binding was identified in both piliated and nonpiliated cells, and is postulated to be mediated by a nonpilin lectin-like adhesin protein.

Original languageEnglish (US)
Pages (from-to)425-430
Number of pages6
JournalAntonie van Leeuwenhoek
Volume53
Issue number6
DOIs
StatePublished - Nov 1 1987
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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    Deal, C. D., Stromberg, N., Nyberg, G., Normark, S., Karlsson, K. A., & So, M. (1987). Pilin independent binding of Neisseria gonorrhoeae to immobilized glycolipids. Antonie van Leeuwenhoek, 53(6), 425-430. https://doi.org/10.1007/BF00415497