Abstract
Development of an erythematous, papulonodular to papulopustular skin eruption in 4 febrile, immunocompromised patients raised the possibility of a systemic mycosis when Gram's stains of unroofed lesions disclosed budding yeasts. Candidiasis, torulopsosis, sporotrichosis, and cryptococcosis were considered in the differential diagnosis, and therapy with amphotericin B was begun. Skin biopsy specimens disclosed fungi to be located exclusively within intact and ruptured hair follicles. Inability of the fungi to grow on media that were not supplemented with lipid and their structure and location all suggested the presence of Pityrosporum sp. When hematogenous dissemination of a mycosis to the skin is suspected, the diagnosis must be based on biopsy specimen demonstration of dermal invasion, ideally with positive cultures. Pityrosporum sp, common skin saprophytes, may produce folliculitis, and be mistaken for pathogenic yeasts.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2126-2129 |
| Number of pages | 4 |
| Journal | Archives of Internal Medicine |
| Volume | 142 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1982 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Internal Medicine
Cite this
Pityrosporum folliculitis. Its potential for confusion with skin lesions of systemic candidiasis. / Klotz, Stephen A; Drutz, D. J.; Huppert, M.; Johnson, J. E.
In: Archives of Internal Medicine, Vol. 142, No. 12, 1982, p. 2126-2129.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pityrosporum folliculitis. Its potential for confusion with skin lesions of systemic candidiasis
AU - Klotz, Stephen A
AU - Drutz, D. J.
AU - Huppert, M.
AU - Johnson, J. E.
PY - 1982
Y1 - 1982
N2 - Development of an erythematous, papulonodular to papulopustular skin eruption in 4 febrile, immunocompromised patients raised the possibility of a systemic mycosis when Gram's stains of unroofed lesions disclosed budding yeasts. Candidiasis, torulopsosis, sporotrichosis, and cryptococcosis were considered in the differential diagnosis, and therapy with amphotericin B was begun. Skin biopsy specimens disclosed fungi to be located exclusively within intact and ruptured hair follicles. Inability of the fungi to grow on media that were not supplemented with lipid and their structure and location all suggested the presence of Pityrosporum sp. When hematogenous dissemination of a mycosis to the skin is suspected, the diagnosis must be based on biopsy specimen demonstration of dermal invasion, ideally with positive cultures. Pityrosporum sp, common skin saprophytes, may produce folliculitis, and be mistaken for pathogenic yeasts.
AB - Development of an erythematous, papulonodular to papulopustular skin eruption in 4 febrile, immunocompromised patients raised the possibility of a systemic mycosis when Gram's stains of unroofed lesions disclosed budding yeasts. Candidiasis, torulopsosis, sporotrichosis, and cryptococcosis were considered in the differential diagnosis, and therapy with amphotericin B was begun. Skin biopsy specimens disclosed fungi to be located exclusively within intact and ruptured hair follicles. Inability of the fungi to grow on media that were not supplemented with lipid and their structure and location all suggested the presence of Pityrosporum sp. When hematogenous dissemination of a mycosis to the skin is suspected, the diagnosis must be based on biopsy specimen demonstration of dermal invasion, ideally with positive cultures. Pityrosporum sp, common skin saprophytes, may produce folliculitis, and be mistaken for pathogenic yeasts.
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U2 - 10.1001/archinte.142.12.2126
DO - 10.1001/archinte.142.12.2126
M3 - Article
C2 - 7138160
AN - SCOPUS:0019960679
VL - 142
SP - 2126
EP - 2129
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 12
ER -