Pityrosporum folliculitis. Its potential for confusion with skin lesions of systemic candidiasis

Stephen A Klotz, D. J. Drutz, M. Huppert, J. E. Johnson

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Development of an erythematous, papulonodular to papulopustular skin eruption in 4 febrile, immunocompromised patients raised the possibility of a systemic mycosis when Gram's stains of unroofed lesions disclosed budding yeasts. Candidiasis, torulopsosis, sporotrichosis, and cryptococcosis were considered in the differential diagnosis, and therapy with amphotericin B was begun. Skin biopsy specimens disclosed fungi to be located exclusively within intact and ruptured hair follicles. Inability of the fungi to grow on media that were not supplemented with lipid and their structure and location all suggested the presence of Pityrosporum sp. When hematogenous dissemination of a mycosis to the skin is suspected, the diagnosis must be based on biopsy specimen demonstration of dermal invasion, ideally with positive cultures. Pityrosporum sp, common skin saprophytes, may produce folliculitis, and be mistaken for pathogenic yeasts.

Original languageEnglish (US)
Pages (from-to)2126-2129
Number of pages4
JournalArchives of Internal Medicine
Volume142
Issue number12
DOIs
StatePublished - 1982
Externally publishedYes

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Malassezia
Folliculitis
Skin
Mycoses
Fungi
Sporotrichosis
Biopsy
Cryptococcosis
Saccharomycetales
Hair Follicle
Candidiasis
Immunocompromised Host
Amphotericin B
Differential Diagnosis
Fever
Yeasts
Systemic candidiasis
Lipids

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Pityrosporum folliculitis. Its potential for confusion with skin lesions of systemic candidiasis. / Klotz, Stephen A; Drutz, D. J.; Huppert, M.; Johnson, J. E.

In: Archives of Internal Medicine, Vol. 142, No. 12, 1982, p. 2126-2129.

Research output: Contribution to journalArticle

Klotz, Stephen A ; Drutz, D. J. ; Huppert, M. ; Johnson, J. E. / Pityrosporum folliculitis. Its potential for confusion with skin lesions of systemic candidiasis. In: Archives of Internal Medicine. 1982 ; Vol. 142, No. 12. pp. 2126-2129.
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