Abstract
Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.
| Original language | English (US) |
|---|---|
| Title of host publication | NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems |
| Pages | 105-108 |
| Number of pages | 4 |
| DOIs | |
| State | Published - 2011 |
| Event | 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan, Province of China Duration: Feb 20 2011 → Feb 23 2011 |
Other
| Other | 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 |
|---|---|
| Country | Taiwan, Province of China |
| City | Kaohsiung |
| Period | 2/20/11 → 2/23/11 |
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Keywords
- cell adhesion
- cell migration
- collective cell behaviors
- complex systems
- plasma lithography
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
Cite this
Plasma lithography for probing collective cell behaviors. / Junkin, Michael; Wong, Pak Kin.
NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 2011. p. 105-108 6017306.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Plasma lithography for probing collective cell behaviors
AU - Junkin, Michael
AU - Wong, Pak Kin
PY - 2011
Y1 - 2011
N2 - Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.
AB - Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.
KW - cell adhesion
KW - cell migration
KW - collective cell behaviors
KW - complex systems
KW - plasma lithography
UR - http://www.scopus.com/inward/record.url?scp=80053309614&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053309614&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2011.6017306
DO - 10.1109/NEMS.2011.6017306
M3 - Conference contribution
AN - SCOPUS:80053309614
SN - 9781612847757
SP - 105
EP - 108
BT - NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
ER -