Plasma lithography for probing collective cell behaviors

Michael Junkin, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.

Original languageEnglish (US)
Title of host publicationNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Pages105-108
Number of pages4
DOIs
StatePublished - Oct 4 2011
Event6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan, Province of China
Duration: Feb 20 2011Feb 23 2011

Publication series

NameNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Other

Other6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
CountryTaiwan, Province of China
CityKaohsiung
Period2/20/112/23/11

Keywords

  • cell adhesion
  • cell migration
  • collective cell behaviors
  • complex systems
  • plasma lithography

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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    Junkin, M., & Wong, P. K. (2011). Plasma lithography for probing collective cell behaviors. In NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (pp. 105-108). [6017306] (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017306