Pleural plaques and asbestos-associated malignancy

Philip I Harber, Z. Mohsenifar, A. Oren, M. Lew

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The large size of the population that has had asbestos exposure makes pleural plaques a frequent health concern for these workers' families, as well as to their employers and to the medical and legal personnel involved. Recent increases in public and health professional awareness of asbestos effects is increasing the vigor with which plaques are sought diagnostically. Previous studies of the significance of pleural plaques have yielded conflicting results. We have therefore conducted a nested case-control study of a cohort of asbestos-exposed workers to determine whether pleural plaques are a risk factor for development of asbestos-associated malignancy. This study found no association between pleural plaques and asbestos-associated malignancies that were independent of other causative factors such as duration of asbestos exposure, age, and cigarette smoking. Although pleural plaques do indicate exposure, we do not believe their presence or absence should be used to allocate cancer screening resources among similarly exposed asbestos workers. If workers are known to have had significant exposure, it appears unwise to deny them appropriate examinations that they might otherwise receive simply because pleural plaque is not detected.

Original languageEnglish (US)
Pages (from-to)641-644
Number of pages4
JournalJournal of Occupational Medicine
Volume29
Issue number8
StatePublished - 1987
Externally publishedYes

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Asbestos
Neoplasms
Population Density
Early Detection of Cancer
Case-Control Studies
Public Health
Smoking
Health

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Harber, P. I., Mohsenifar, Z., Oren, A., & Lew, M. (1987). Pleural plaques and asbestos-associated malignancy. Journal of Occupational Medicine, 29(8), 641-644.

Pleural plaques and asbestos-associated malignancy. / Harber, Philip I; Mohsenifar, Z.; Oren, A.; Lew, M.

In: Journal of Occupational Medicine, Vol. 29, No. 8, 1987, p. 641-644.

Research output: Contribution to journalArticle

Harber, PI, Mohsenifar, Z, Oren, A & Lew, M 1987, 'Pleural plaques and asbestos-associated malignancy', Journal of Occupational Medicine, vol. 29, no. 8, pp. 641-644.
Harber, Philip I ; Mohsenifar, Z. ; Oren, A. ; Lew, M. / Pleural plaques and asbestos-associated malignancy. In: Journal of Occupational Medicine. 1987 ; Vol. 29, No. 8. pp. 641-644.
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