Post-procedure surveillance in liver biopsy

How long is long enough?

Rowena Howard, George Karageorge, Kate van Harselaar, Melanie L Bell, Pete Basford, Michael Schultz, Sarah Derrett

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Aim: To assess the incidence of complications following liver biopsy and the impact of pre-procedural pethidine on complications and analgesia administration. Method: A retrospective audit of percutaneous liver biopsies undertaken at Dunedin Public Hospital (2001-2006). Patients' medical files were consulted for demographics, biopsy indication, complications, frequency, and timing of analgesia. Results: 447 biopsies were analysed. Primary indications included: hepatitis C (38.8%), abnormal liver function tests (18.3%), methotrexate therapy (12.5%), and malignancy (10.3%). 303 (68%) biopsies resulted in no complications. Major complications were not experienced. Minor complications included: pain (32.2%), hypotension (1.3%), nausea/ vomiting (0.9%), and alcohol withdrawal (0.2%). More females (47%) than males (31%) reported complications. Post-procedural analgesia was administered in 31% of biopsies; only 9% required analgesia more than 2 hours after biopsy. Patients who had pre-procedural pethidine experienced similar rates of complications as patients not receiving pre-procedural pethidine, but received less post-procedural opiate analgesia. Conclusion: No major complications occurred, whilst the rate of minor complications was comparable with previous studies. Pain was the most common complication, although use of analgesia after 2 hours of observation was low. Our findings suggest that post-procedural observation may safely be reduced to two hours but it is currently unknown if early mobilisation following discharge will lead to complications.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalNew Zealand Medical Journal
Volume121
Issue number1280
StatePublished - Aug 22 2008
Externally publishedYes

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Analgesia
Biopsy
Liver
Meperidine
Opiate Alkaloids
Observation
Pain
Early Ambulation
Public Hospitals
Liver Function Tests
Hepatitis C
Methotrexate
Hypotension
Nausea
Vomiting
Alcohols
Demography
Incidence
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Howard, R., Karageorge, G., van Harselaar, K., Bell, M. L., Basford, P., Schultz, M., & Derrett, S. (2008). Post-procedure surveillance in liver biopsy: How long is long enough? New Zealand Medical Journal, 121(1280), 8-14.

Post-procedure surveillance in liver biopsy : How long is long enough? / Howard, Rowena; Karageorge, George; van Harselaar, Kate; Bell, Melanie L; Basford, Pete; Schultz, Michael; Derrett, Sarah.

In: New Zealand Medical Journal, Vol. 121, No. 1280, 22.08.2008, p. 8-14.

Research output: Contribution to journalArticle

Howard, R, Karageorge, G, van Harselaar, K, Bell, ML, Basford, P, Schultz, M & Derrett, S 2008, 'Post-procedure surveillance in liver biopsy: How long is long enough?', New Zealand Medical Journal, vol. 121, no. 1280, pp. 8-14.
Howard R, Karageorge G, van Harselaar K, Bell ML, Basford P, Schultz M et al. Post-procedure surveillance in liver biopsy: How long is long enough? New Zealand Medical Journal. 2008 Aug 22;121(1280):8-14.
Howard, Rowena ; Karageorge, George ; van Harselaar, Kate ; Bell, Melanie L ; Basford, Pete ; Schultz, Michael ; Derrett, Sarah. / Post-procedure surveillance in liver biopsy : How long is long enough?. In: New Zealand Medical Journal. 2008 ; Vol. 121, No. 1280. pp. 8-14.
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