Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center: a Case Series and Review of the Literature

Joseph David Cooper, Surya Ram Cooper, Donna Wolk, Ann Marie Tice, Tamara F. Persing, Lisa Marie Esolen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Historically, childbirth was associated with morbidity and mortality, often due to endometritis or puerperal fever. Streptococcus pyogenes was first identified as the cause of puerperal fever by Louis Pasteur, and it remains a virulent and lethal pathogen with a case fatality rate of 15 to 20% [1]. The pathogenesis of postpartum endometritis is believed to be associated with disruption of the woman's mucosal barriers from childbirth and invasion of bacteria either from vaginal flora or from a health care worker's hands [2]. Despite the implementation of hand sanitizing and barrier precautions (gloves), outbreaks of S. pyogenes still occur today [1]. This article provides an overview of the role of S. pyogenes in postpartum infections and describes an outbreak of postpartum endometritis due to S. pyogenes. The case report involved three patients who were admitted to a quaternary care medical center on the same day and, following discharge, were all readmitted with sepsis and endometritis. The bacteria were isolated, and pulsed-field gel electrophoresis revealed that the three S. pyogenes strains were genetically identical.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
JournalClinical Microbiology Newsletter
Volume39
Issue number2
DOIs
StatePublished - Jan 15 2017
Externally publishedYes

Fingerprint

Streptococcus pyogenes
Endometritis
Postpartum Period
Disease Outbreaks
Referral and Consultation
Fever
Hand
Parturition
Bacteria
Mortality
Pulsed Field Gel Electrophoresis
Sepsis
Morbidity
Delivery of Health Care
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center : a Case Series and Review of the Literature. / Cooper, Joseph David; Cooper, Surya Ram; Wolk, Donna; Tice, Ann Marie; Persing, Tamara F.; Esolen, Lisa Marie.

In: Clinical Microbiology Newsletter, Vol. 39, No. 2, 15.01.2017, p. 11-15.

Research output: Contribution to journalArticle

Cooper, Joseph David ; Cooper, Surya Ram ; Wolk, Donna ; Tice, Ann Marie ; Persing, Tamara F. ; Esolen, Lisa Marie. / Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center : a Case Series and Review of the Literature. In: Clinical Microbiology Newsletter. 2017 ; Vol. 39, No. 2. pp. 11-15.
@article{8ed6c6c50e864bef913ab579dc3cb322,
title = "Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center: a Case Series and Review of the Literature",
abstract = "Historically, childbirth was associated with morbidity and mortality, often due to endometritis or puerperal fever. Streptococcus pyogenes was first identified as the cause of puerperal fever by Louis Pasteur, and it remains a virulent and lethal pathogen with a case fatality rate of 15 to 20{\%} [1]. The pathogenesis of postpartum endometritis is believed to be associated with disruption of the woman's mucosal barriers from childbirth and invasion of bacteria either from vaginal flora or from a health care worker's hands [2]. Despite the implementation of hand sanitizing and barrier precautions (gloves), outbreaks of S. pyogenes still occur today [1]. This article provides an overview of the role of S. pyogenes in postpartum infections and describes an outbreak of postpartum endometritis due to S. pyogenes. The case report involved three patients who were admitted to a quaternary care medical center on the same day and, following discharge, were all readmitted with sepsis and endometritis. The bacteria were isolated, and pulsed-field gel electrophoresis revealed that the three S. pyogenes strains were genetically identical.",
author = "Cooper, {Joseph David} and Cooper, {Surya Ram} and Donna Wolk and Tice, {Ann Marie} and Persing, {Tamara F.} and Esolen, {Lisa Marie}",
year = "2017",
month = "1",
day = "15",
doi = "10.1016/j.clinmicnews.2016.12.003",
language = "English (US)",
volume = "39",
pages = "11--15",
journal = "Clinical Microbiology Newsletter",
issn = "0196-4399",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center

T2 - a Case Series and Review of the Literature

AU - Cooper, Joseph David

AU - Cooper, Surya Ram

AU - Wolk, Donna

AU - Tice, Ann Marie

AU - Persing, Tamara F.

AU - Esolen, Lisa Marie

PY - 2017/1/15

Y1 - 2017/1/15

N2 - Historically, childbirth was associated with morbidity and mortality, often due to endometritis or puerperal fever. Streptococcus pyogenes was first identified as the cause of puerperal fever by Louis Pasteur, and it remains a virulent and lethal pathogen with a case fatality rate of 15 to 20% [1]. The pathogenesis of postpartum endometritis is believed to be associated with disruption of the woman's mucosal barriers from childbirth and invasion of bacteria either from vaginal flora or from a health care worker's hands [2]. Despite the implementation of hand sanitizing and barrier precautions (gloves), outbreaks of S. pyogenes still occur today [1]. This article provides an overview of the role of S. pyogenes in postpartum infections and describes an outbreak of postpartum endometritis due to S. pyogenes. The case report involved three patients who were admitted to a quaternary care medical center on the same day and, following discharge, were all readmitted with sepsis and endometritis. The bacteria were isolated, and pulsed-field gel electrophoresis revealed that the three S. pyogenes strains were genetically identical.

AB - Historically, childbirth was associated with morbidity and mortality, often due to endometritis or puerperal fever. Streptococcus pyogenes was first identified as the cause of puerperal fever by Louis Pasteur, and it remains a virulent and lethal pathogen with a case fatality rate of 15 to 20% [1]. The pathogenesis of postpartum endometritis is believed to be associated with disruption of the woman's mucosal barriers from childbirth and invasion of bacteria either from vaginal flora or from a health care worker's hands [2]. Despite the implementation of hand sanitizing and barrier precautions (gloves), outbreaks of S. pyogenes still occur today [1]. This article provides an overview of the role of S. pyogenes in postpartum infections and describes an outbreak of postpartum endometritis due to S. pyogenes. The case report involved three patients who were admitted to a quaternary care medical center on the same day and, following discharge, were all readmitted with sepsis and endometritis. The bacteria were isolated, and pulsed-field gel electrophoresis revealed that the three S. pyogenes strains were genetically identical.

UR - http://www.scopus.com/inward/record.url?scp=85009135103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85009135103&partnerID=8YFLogxK

U2 - 10.1016/j.clinmicnews.2016.12.003

DO - 10.1016/j.clinmicnews.2016.12.003

M3 - Article

AN - SCOPUS:85009135103

VL - 39

SP - 11

EP - 15

JO - Clinical Microbiology Newsletter

JF - Clinical Microbiology Newsletter

SN - 0196-4399

IS - 2

ER -