Postresuscitation myocardial dysfunction

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Postresuscitation myocardial dysfunction is common after prolonged cardiac arrest and can have life-threatening consequences. Experimental data suggest that systolic and diastolic left ventricular function can be adversely effected following successful resuscitation. Such dysfunction can resolve and represents true global myocardial stunning. Identified factors contributing to postresuscitation myocardial dysfunction include prolonged CPR, use of vasoconstricting drugs, and high-energy defibrillation. Potential treatments include dobutamine, KATP channel activators, and 21-aminosteroids. In the author's efforts to improve long-term survival from cardiac arrest, more attention is needed to the postresuscitation period.

Original languageEnglish (US)
Pages (from-to)89-101
Number of pages13
JournalCardiology Clinics
Volume20
Issue number1
DOIs
StatePublished - 2002

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Heart Arrest
Myocardial Stunning
KATP Channels
Dobutamine
Cardiopulmonary Resuscitation
Left Ventricular Function
Resuscitation
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Postresuscitation myocardial dysfunction. / Kern, Karl B.

In: Cardiology Clinics, Vol. 20, No. 1, 2002, p. 89-101.

Research output: Contribution to journalArticle

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