Practice guidelines for the treatment of coccidioidomycosis

John N. Galgiani, Neil M. Ampel, Antonino Catanzaro, Royce H. Johnson, David A. Stevens, Paul L. Williams

Research output: Contribution to journalReview article

234 Scopus citations

Abstract

Management of patients diagnosed with coccidioidomycosis involves defining the extent of infection and assessing host factors that predispose to disease severity. Patients with relatively localized acute pulmonary infections and no risk factors for complications often require only periodic reassessment to demonstrate resolution of their self-limited process. On the other hand, patients with extensive spread of infection or at a high risk of complications because of immunosuppresion or other pre-existing factors require a variety of treatment strategies that may include antifungal therapy, surgical debridement, or both. Amphotericin B is often selected for treatment of patients with respiratory failure due to Coccidioides immitis or rapidly progressive coccidioidal infections. With other more chronic manifestations of coccidioidomysis, treatment with fluconazole, itraconazole, or ketoconazole is common. Duration of therapy often ranges from many months to years, and, for some patients, chronic suppressive therapy is needed to prevent relapses.

Original languageEnglish (US)
Pages (from-to)658-661
Number of pages4
JournalClinical Infectious Diseases
Volume30
Issue number4
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Practice guidelines for the treatment of coccidioidomycosis'. Together they form a unique fingerprint.

  • Cite this