Prediction of symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage with an artificial neural network: Feasibility and comparison with logistic regression models

Travis M. Dumont, Anand I. Rughani, Bruce I. Tranmer

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Objective To create a simple artificial neural network (ANN) to predict the occurrence of symptomatic cerebral vasospasm (SCV) after aneurysmal subarachnoid hemorrhage (aSAH) based on clinical and radiographic factors and test its predictive ability against existing multiple logistic regression (MLR) models. Methods A retrospective database of patients admitted to a single academic medical center with confirmed aSAH between January 2002 and January 2007 (91 patients) was input to a back-propagation ANN program freely available to academicians on the Internet. The resulting ANN was prospectively tested against two previously published MLR prediction models for all patients admitted the following year (22 patients). The models were compared for their predictive accuracy with receiver operating characteristic (ROC) curve analysis. Results All models were accurate with their prediction of patients with SCV. The ANN had superior predictive value compared with the MLR models, with a significantly improved area under ROC curve (0.960 ± 0.044 vs 0.933 ± 0.54 and 0.897 ± 0.069 for MLR models). Conclusions A simple ANN model was more sensitive and specific than MLR models in prediction of SCV in patients with aSAH. The conception of ANN modeling for cerebral vasospasm is introduced for a neurosurgical audience. With advanced ANN modeling, the clinician may expect to build improved models with more powerful prediction capabilities.

Original languageEnglish (US)
Pages (from-to)57-63
Number of pages7
JournalWorld neurosurgery
Volume75
Issue number1
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

Keywords

  • Cerebral vasospasm
  • Neural network
  • Neurosurgery
  • Subarachnoid hemorrhage

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Prediction of symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage with an artificial neural network: Feasibility and comparison with logistic regression models'. Together they form a unique fingerprint.

  • Cite this