Abstract
Background: Pre-menstrual dysphoric disorder (PMDD), a dysphoric form of pre-menstrual syndrome, is included as a diagnosis for further study in the DSM-IV-TR (APA, 2000). The present study investigated whether a marker of risk for major depressive disorder (MDD), prefrontal brain asymmetry, also characterizes women with PMDD. Methods: In a sample of 25 college women with PMDD symptomatology and 25 matched controls, resting frontal electroencephalographic (EEG) activity was assessed on four occasions within a two-week span. Results: Across several frontal sites women with PMDD had relatively less left than right prefrontal brain activity, consistent with a diathesis-stress model for menstrual-related dysphoria. Conclusions: The findings suggest an overlap in the risk profile for MDD and PMDD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 178-183 |
| Number of pages | 6 |
| Journal | Journal of Affective Disorders |
| Volume | 128 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 2011 |
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Keywords
- Diathesis
- EEG asymmetry
- Pre-menstrual dysphoria
- Risk
ASJC Scopus subject areas
- Psychiatry and Mental health
- Clinical Psychology
Cite this
Prefrontal brain asymmetry and pre-menstrual dysphoric disorder symptomatology. / Accortt, Eynav E.; Stewart, Jennifer L.; Coan, James A.; Manber, Rachel; Allen, John JB.
In: Journal of Affective Disorders, Vol. 128, No. 1-2, 01.2011, p. 178-183.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prefrontal brain asymmetry and pre-menstrual dysphoric disorder symptomatology
AU - Accortt, Eynav E.
AU - Stewart, Jennifer L.
AU - Coan, James A.
AU - Manber, Rachel
AU - Allen, John JB
PY - 2011/1
Y1 - 2011/1
N2 - Background: Pre-menstrual dysphoric disorder (PMDD), a dysphoric form of pre-menstrual syndrome, is included as a diagnosis for further study in the DSM-IV-TR (APA, 2000). The present study investigated whether a marker of risk for major depressive disorder (MDD), prefrontal brain asymmetry, also characterizes women with PMDD. Methods: In a sample of 25 college women with PMDD symptomatology and 25 matched controls, resting frontal electroencephalographic (EEG) activity was assessed on four occasions within a two-week span. Results: Across several frontal sites women with PMDD had relatively less left than right prefrontal brain activity, consistent with a diathesis-stress model for menstrual-related dysphoria. Conclusions: The findings suggest an overlap in the risk profile for MDD and PMDD.
AB - Background: Pre-menstrual dysphoric disorder (PMDD), a dysphoric form of pre-menstrual syndrome, is included as a diagnosis for further study in the DSM-IV-TR (APA, 2000). The present study investigated whether a marker of risk for major depressive disorder (MDD), prefrontal brain asymmetry, also characterizes women with PMDD. Methods: In a sample of 25 college women with PMDD symptomatology and 25 matched controls, resting frontal electroencephalographic (EEG) activity was assessed on four occasions within a two-week span. Results: Across several frontal sites women with PMDD had relatively less left than right prefrontal brain activity, consistent with a diathesis-stress model for menstrual-related dysphoria. Conclusions: The findings suggest an overlap in the risk profile for MDD and PMDD.
KW - Diathesis
KW - EEG asymmetry
KW - Pre-menstrual dysphoria
KW - Risk
UR - http://www.scopus.com/inward/record.url?scp=78649661557&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649661557&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2010.07.017
DO - 10.1016/j.jad.2010.07.017
M3 - Article
C2 - 20833433
AN - SCOPUS:78649661557
VL - 128
SP - 178
EP - 183
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
SN - 0165-0327
IS - 1-2
ER -