Preliminary evaluation of surface mesh modeling of system geometry, anatomy phantom, and source activity for GATE simulations

Benjamin Auer, Arda Könik, Kesava Kalluri, Jan De Beenhouwer, Lars R. Furenlid, Michael A. King

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Simulation studies have been essential for development of SPECT imaging systems. GATE is one of the most commonly used simulation toolkits in nuclear medicine. This software package allows the users to build system geometries and phantoms based on primitive objects such as cylinder, sphere, and cube. However, modeling systems with complex geometry is challenging, if not impossible using these primitive volumes. The latest GATE release addressed this issue by allowing the users to import surface meshes created in a computer aided design software thus enabling accurate simulation of complex system or phantom geometries. In this study we present our GATE mesh-based simulations of a next-generation multi-pinhole SPECT system for the clinical brain imaging, called AdaptiSPECT-C. An additional challenge with the AdaptiSPECT-C is that the volume of the standard voxelized XCAT phantom overlaps with the spherical collimator plate. In order to address this issue, we developed a mesh modeling of the XCAT human phantom by directly using the native XCAT nurbs data, which also provided a more accurate representation of the anatomy. Two approaches for simulating mesh-based activity source were developed and evaluated. The first method consisted of using an acceptance/rejection criterion confining a cubical source into the mesh object and the second one was based on a conversion of a mesh-based volume into a voxelized object. Although the two strategies led to very similar results, the voxelized-mesh approach was significantly faster in computation time. We successfully imported and simulated in GATE a complete SPECT acquisition incorporating an STL representation of system, phantom anatomy, and activity source.

Original languageEnglish (US)
Title of host publication2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538684948
DOIs
StatePublished - Nov 2018
Event2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Sydney, Australia
Duration: Nov 10 2018Nov 17 2018

Publication series

Name2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings

Conference

Conference2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018
CountryAustralia
CitySydney
Period11/10/1811/17/18

Keywords

  • GATE simulation toolkit
  • Simulation of complex system/phantom geometries
  • XCAT human phantom
  • computer aided design software
  • mesh-based representation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Nuclear and High Energy Physics

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