Preliminary investigation of design parameters of an innovative multi-pinhole system dedicated to brain SPECT imaging

Benjamin Auer, Jan De Beenhouwer, Kesava Kalluri, Justin C. Goding, Lars R. Furenlid, Michael A. King

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Collimator penetration, down-scatter related to 123I high energy photons, and scatter within detectors can significantly degrade the imaging performance of any system. Precise selection of pinhole and collimator parameters using simulation studies has the potential to considerably reduce these effects. This type of investigation, thus represents an essential step in system development. An innovative multi-pinhole system, AdaptiSPECT-C, dedicated to clinical brain SPECT imaging, is currently under development at the universities of Massachusetts and Arizona. The aim of this work was to determine the system parameters which considerably improve AdaptiSPECT- C imaging performance for the criteria of sensitivity and relative amounts of scatter and penetration. A 20 mm thick, tungsten alloy collimator leads to the best trade-off between performance and price in case of 123I imaging. Tungsten alloy provided performance relatively close to that of gold in terms of stopping power as compared to lead alloy. A pinhole center distance of 0.5 cm to the aperture entry port led to the best compromise for locating the aperture within the aperture plate in terms of sensitivity and relative amounts of scatter and penetration.

Original languageEnglish (US)
Title of host publication2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538684948
DOIs
StatePublished - Nov 2018
Externally publishedYes
Event2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Sydney, Australia
Duration: Nov 10 2018Nov 17 2018

Publication series

Name2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings

Conference

Conference2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018
CountryAustralia
CitySydney
Period11/10/1811/17/18

Keywords

  • I SPECT imaging
  • Optimization study
  • effects degrading imaging performance
  • next-generation clinical system

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Nuclear and High Energy Physics

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    Auer, B., Beenhouwer, J. D., Kalluri, K., Goding, J. C., Furenlid, L. R., & King, M. A. (2018). Preliminary investigation of design parameters of an innovative multi-pinhole system dedicated to brain SPECT imaging. In 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings [8824691] (2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2018 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2018.8824691