Preliminary study of the tryptase levels in the synovial fluid of patients with inflammatory arthritis

J. P. Lavery, J. R. Lisse

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

This study examined levels of tryptase, a specific mast cell product, in synovial fluid. Samples of synovial fluid from eight patients with rheumatoid arthritis and ten with other arthritides were measured in solid-phase immunoradiometric assays. Elevated concentrations of tryptase were present in samples from three patients with rheumatoid arthritis, one with psoriasis, and one with Reiter's syndrome. The data support the theory that mast cell activation is involved in the pathogenesis in some inflammatory joint diseases, but activation does not appear to be disease specific.

Original languageEnglish (US)
Pages (from-to)425-427
Number of pages3
JournalAnnals of Allergy
Volume72
Issue number5
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Immunology and Allergy

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