Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose

Robert B. Hawkins, Helena L. Frischtak, Irving L. Kron, Ravi K. Ghanta

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We present the cases of two patients with bioprosthetic aortic valves who developed an allergy to alpha-gal. Each had premature degeneration of their bioprosthesis and demonstrated rapidly increasing transvalvular gradients after development of their allergy. Each underwent successful replacement with a mechanical aortic valve within 1–2 years of symptom onset. doi: 10.1111/jocs.12764 (J Card Surg 2016;31:446–448).

Original languageEnglish (US)
Pages (from-to)446-448
Number of pages3
JournalJournal of Cardiac Surgery
Volume31
Issue number7
DOIs
StatePublished - Jul 1 2016
Externally publishedYes

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Aortic Valve
Hypersensitivity
Bioprosthesis
galactosyl-(1-3)galactose

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose. / Hawkins, Robert B.; Frischtak, Helena L.; Kron, Irving L.; Ghanta, Ravi K.

In: Journal of Cardiac Surgery, Vol. 31, No. 7, 01.07.2016, p. 446-448.

Research output: Contribution to journalArticle

Hawkins, Robert B. ; Frischtak, Helena L. ; Kron, Irving L. ; Ghanta, Ravi K. / Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose. In: Journal of Cardiac Surgery. 2016 ; Vol. 31, No. 7. pp. 446-448.
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