Prevalence of mitral valve prolapse and associated valvular regurgitations in healthy teenagers undergoing screening echocardiography

Sudhakar Sattur, Sharon Bates, Mohammad R Movahed

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

BackgRound: The true prevalence of mitral valve prolapse (MVP) in the population has been controversial. oBjective: To evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students. Methods: The Anthony Bates Foundation performed screening echocardiography in high schools across the United States. A total of 2072 students between 13 and 19 years of age were identified for the present study. Results: Total prevalence of MVP was 0.7%. The prevalence of MVP was significantly higher among female teenagers (nine of 690 female teenagers [1.3%] versus five of 1382 male teenagers [0.4%], P=0.01, OR 3.6, CI 1.21 to 10.70). The prevalence of mitral regurgitation (MR) and tricuspid regurgitation (TR) was higher in teenagers with MVP. MR occurred in five of 14 teenagers (35.7%) with MVP versus 15 of 2058 controls (0.7%) (P<0.001, OR 75.6, CI 22.6 to 252.5). TR occurred in one of 14 teenagers (7.1%) with MVP versus nine of 2058 controls (0.4%) (P<0.001, OR 17.5, CI 2.0 to 148.3). conclusion: The prevalence of MVP in this cohort of healthy teenage students was less than 1%. Furthermore, the prevalence of MVP was higher in female teenagers and was associated with a higher prevalence of MR and TR.

Original languageEnglish (US)
JournalExperimental and Clinical Cardiology
Volume15
Issue number1
StatePublished - Mar 2010

Fingerprint

Mitral Valve Prolapse
Echocardiography
Tricuspid Valve Insufficiency
Mitral Valve Insufficiency
Students

Keywords

  • Adolescence
  • Mitral valvar prolapse
  • MVP
  • Screening
  • Teenagers
  • Valvular disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Physiology

Cite this

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title = "Prevalence of mitral valve prolapse and associated valvular regurgitations in healthy teenagers undergoing screening echocardiography",
abstract = "BackgRound: The true prevalence of mitral valve prolapse (MVP) in the population has been controversial. oBjective: To evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students. Methods: The Anthony Bates Foundation performed screening echocardiography in high schools across the United States. A total of 2072 students between 13 and 19 years of age were identified for the present study. Results: Total prevalence of MVP was 0.7{\%}. The prevalence of MVP was significantly higher among female teenagers (nine of 690 female teenagers [1.3{\%}] versus five of 1382 male teenagers [0.4{\%}], P=0.01, OR 3.6, CI 1.21 to 10.70). The prevalence of mitral regurgitation (MR) and tricuspid regurgitation (TR) was higher in teenagers with MVP. MR occurred in five of 14 teenagers (35.7{\%}) with MVP versus 15 of 2058 controls (0.7{\%}) (P<0.001, OR 75.6, CI 22.6 to 252.5). TR occurred in one of 14 teenagers (7.1{\%}) with MVP versus nine of 2058 controls (0.4{\%}) (P<0.001, OR 17.5, CI 2.0 to 148.3). conclusion: The prevalence of MVP in this cohort of healthy teenage students was less than 1{\%}. Furthermore, the prevalence of MVP was higher in female teenagers and was associated with a higher prevalence of MR and TR.",
keywords = "Adolescence, Mitral valvar prolapse, MVP, Screening, Teenagers, Valvular disease",
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AU - Sattur, Sudhakar

AU - Bates, Sharon

AU - Movahed, Mohammad R

PY - 2010/3

Y1 - 2010/3

N2 - BackgRound: The true prevalence of mitral valve prolapse (MVP) in the population has been controversial. oBjective: To evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students. Methods: The Anthony Bates Foundation performed screening echocardiography in high schools across the United States. A total of 2072 students between 13 and 19 years of age were identified for the present study. Results: Total prevalence of MVP was 0.7%. The prevalence of MVP was significantly higher among female teenagers (nine of 690 female teenagers [1.3%] versus five of 1382 male teenagers [0.4%], P=0.01, OR 3.6, CI 1.21 to 10.70). The prevalence of mitral regurgitation (MR) and tricuspid regurgitation (TR) was higher in teenagers with MVP. MR occurred in five of 14 teenagers (35.7%) with MVP versus 15 of 2058 controls (0.7%) (P<0.001, OR 75.6, CI 22.6 to 252.5). TR occurred in one of 14 teenagers (7.1%) with MVP versus nine of 2058 controls (0.4%) (P<0.001, OR 17.5, CI 2.0 to 148.3). conclusion: The prevalence of MVP in this cohort of healthy teenage students was less than 1%. Furthermore, the prevalence of MVP was higher in female teenagers and was associated with a higher prevalence of MR and TR.

AB - BackgRound: The true prevalence of mitral valve prolapse (MVP) in the population has been controversial. oBjective: To evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students. Methods: The Anthony Bates Foundation performed screening echocardiography in high schools across the United States. A total of 2072 students between 13 and 19 years of age were identified for the present study. Results: Total prevalence of MVP was 0.7%. The prevalence of MVP was significantly higher among female teenagers (nine of 690 female teenagers [1.3%] versus five of 1382 male teenagers [0.4%], P=0.01, OR 3.6, CI 1.21 to 10.70). The prevalence of mitral regurgitation (MR) and tricuspid regurgitation (TR) was higher in teenagers with MVP. MR occurred in five of 14 teenagers (35.7%) with MVP versus 15 of 2058 controls (0.7%) (P<0.001, OR 75.6, CI 22.6 to 252.5). TR occurred in one of 14 teenagers (7.1%) with MVP versus nine of 2058 controls (0.4%) (P<0.001, OR 17.5, CI 2.0 to 148.3). conclusion: The prevalence of MVP in this cohort of healthy teenage students was less than 1%. Furthermore, the prevalence of MVP was higher in female teenagers and was associated with a higher prevalence of MR and TR.

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